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The future of HIV-1 therapeutics = r...

Torbett, Bruce E.

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The future of HIV-1 therapeutics = resistance is futile? /

Record Type:	Electronic resources : Monograph/item
Title/Author:	The future of HIV-1 therapeutics/ edited by Bruce E. Torbett, David S. Goodsell, Douglas D. Richman.
Reminder of title:	resistance is futile? /
other author:	Torbett, Bruce E.
Published:	Cham :Springer International Publishing : : 2015.,
Description:	x, 254 p. :ill., digital ;24 cm.
[NT 15003449]:	HIV Therapy Looking Towards the Future -- Computational challenges of structure-based approaches applied to HIV -- Nucleocapsid Protein: A Desirable Target For Future Therapies Against HIV-1 -- HIV-1 integrase multimerization as a therapeutic target -- Targeting HIV transcription: The quest for a functional cure -- Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer Ladder -- HIV-1 Gag: An Emerging Target for Antiretroviral Therapy -- The Triple Threat of HIV-1 Protease Inhibitors -- Illustrations of the HIV Life Cycle.
Contained By:	Springer eBooks
Subject:	Antiviral agents. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-18518-7
ISBN:	9783319185187 (electronic bk.)

The future of HIV-1 therapeutics = resistance is futile? /
The future of HIV-1 therapeuticsresistance is futile? /[electronic resource] :edited by Bruce E. Torbett, David S. Goodsell, Douglas D. Richman. - Cham :Springer International Publishing :2015. - x, 254 p. :ill., digital ;24 cm. - Current topics in microbiology and immunology,v.3890070-217X ;. - Current topics in microbiology and immunology ;v.351..

HIV Therapy Looking Towards the Future -- Computational challenges of structure-based approaches applied to HIV -- Nucleocapsid Protein: A Desirable Target For Future Therapies Against HIV-1 -- HIV-1 integrase multimerization as a therapeutic target -- Targeting HIV transcription: The quest for a functional cure -- Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer Ladder -- HIV-1 Gag: An Emerging Target for Antiretroviral Therapy -- The Triple Threat of HIV-1 Protease Inhibitors -- Illustrations of the HIV Life Cycle.

This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.

ISBN: 9783319185187 (electronic bk.)

Standard No.: 10.1007/978-3-319-18518-7doiSubjects--Topical Terms:

705874
Antiviral agents.

LC Class. No.: RA643.8

Dewey Class. No.: 614.599392

The future of HIV-1 therapeutics = resistance is futile? /
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505 0 $a HIV Therapy Looking Towards the Future -- Computational challenges of structure-based approaches applied to HIV -- Nucleocapsid Protein: A Desirable Target For Future Therapies Against HIV-1 -- HIV-1 integrase multimerization as a therapeutic target -- Targeting HIV transcription: The quest for a functional cure -- Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer Ladder -- HIV-1 Gag: An Emerging Target for Antiretroviral Therapy -- The Triple Threat of HIV-1 Protease Inhibitors -- Illustrations of the HIV Life Cycle.
520 $a This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.
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700 1 $a Torbett, Bruce E. $3 2145162
700 1 $a Goodsell, David S. $3 748903
700 1 $a Richman, Douglas D. $3 750143
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