東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Protein kinase CK2 cellular function...

Ahmed, Khalil.

FindBook

Google Book

Amazon

博客來

Protein kinase CK2 cellular function in normal and disease states

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Protein kinase CK2 cellular function in normal and disease states/ edited by Khalil Ahmed, Olaf-Georg Issinger, Ryszard Szyszka.
其他作者:	Ahmed, Khalil.
出版者:	Cham :Springer International Publishing : : 2015.,
面頁冊數:	xxiii, 378 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Protein kinase CK2. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-14544-0
ISBN:	9783319145440 (electronic bk.)

Protein kinase CK2 cellular function in normal and disease states
Protein kinase CK2 cellular function in normal and disease states[electronic resource] /edited by Khalil Ahmed, Olaf-Georg Issinger, Ryszard Szyszka. - Cham :Springer International Publishing :2015. - xxiii, 378 p. :ill., digital ;24 cm. - Advances in biochemistry in health and disease ;v.12. - Advances in biochemistry in health and disease ;v.8..

The field of protein kinases has greatly impacted our understanding of the basic mechanisms in cell function. The field has also been a major focus of drug development that considers the broad reach of the protein kinase function under diverse conditions. One member of the kinome, protein kinase CK2, continues to emerge as a major signaling molecule involved in diverse functions in health and disease. This kinase has unique features, most notably its ubiquitous and highly conserved nature. Its vast number of potential substrates exemplifies its involvement in various functions in cells under both the normal and diseased states. Of particular note is the observation that due to its ubiquitous nature, CK2 has been found to be dysregulated in all cancers that have been examined. As such, it is now being considered a potentially important target for cancer therapy. Protein Kinase CK2 plays equally important functions in development and intracellular activities, and has a global impact on cell growth and proliferation. An additional key function of CK2 is the impact of its activity on cell death processes. Given the vast nature of its functions, CK2 has been proposed to serve as a "master regulator" of cell function. The chapters included in this work cover a wide range of topics dealing with some of the functions mentioned above, providing an important starting point for research investigators and graduate students interested in this field.

ISBN: 9783319145440 (electronic bk.)

Standard No.: 10.1007/978-3-319-14544-0doiSubjects--Topical Terms:

2084912
Protein kinase CK2.

LC Class. No.: QP606.P76

Dewey Class. No.: 612.015756

Protein kinase CK2 cellular function in normal and disease states
LDR:02516nmm a2200313 a 4500 001 1997704
003 DE-He213
005 20151008092242.0
006 m d
007 cr nn 008maaau
008 151112s2015 gw s 0 eng d
020 $a 9783319145440 (electronic bk.)
020 $a 9783319145433 (paper)
024 7 $a 10.1007/978-3-319-14544-0 $2 doi
035 $a 978-3-319-14544-0
040 $a GP $c GP
041 0 $a eng
050 4 $a QP606.P76
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
082 0 4 $a 612.015756 $2 23
090 $a QP606.P76 $b P967 2015
245 0 0 $a Protein kinase CK2 cellular function in normal and disease states $h [electronic resource] / $c edited by Khalil Ahmed, Olaf-Georg Issinger, Ryszard Szyszka.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2015.
300 $a xxiii, 378 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in biochemistry in health and disease ; $v v.12
520 $a The field of protein kinases has greatly impacted our understanding of the basic mechanisms in cell function. The field has also been a major focus of drug development that considers the broad reach of the protein kinase function under diverse conditions. One member of the kinome, protein kinase CK2, continues to emerge as a major signaling molecule involved in diverse functions in health and disease. This kinase has unique features, most notably its ubiquitous and highly conserved nature. Its vast number of potential substrates exemplifies its involvement in various functions in cells under both the normal and diseased states. Of particular note is the observation that due to its ubiquitous nature, CK2 has been found to be dysregulated in all cancers that have been examined. As such, it is now being considered a potentially important target for cancer therapy. Protein Kinase CK2 plays equally important functions in development and intracellular activities, and has a global impact on cell growth and proliferation. An additional key function of CK2 is the impact of its activity on cell death processes. Given the vast nature of its functions, CK2 has been proposed to serve as a "master regulator" of cell function. The chapters included in this work cover a wide range of topics dealing with some of the functions mentioned above, providing an important starting point for research investigators and graduate students interested in this field.
650 0 $a Protein kinase CK2. $3 2084912
650 1 4 $a Biomedicine. $3 890831
650 2 4 $a Cancer Research. $3 891172
650 2 4 $a Protein Science. $3 1067276
650 2 4 $a Apoptosis. $3 600650
700 1 $a Ahmed, Khalil. $3 2139015
700 1 $a Issinger, Olaf-Georg. $3 2139016
700 1 $a Szyszka, Ryszard. $3 2139017
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a Advances in biochemistry in health and disease ; $v v.8. $3 2056426
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-14544-0
950 $a Biomedical and Life Sciences (Springer-11642)