東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Receptor tyrosine kinases = structur...

Wheeler, Deric L.

FindBook

Google Book

Amazon

博客來

Receptor tyrosine kinases = structure, functions and role in human disease /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Receptor tyrosine kinases/ edited by Deric L. Wheeler, Yosef Yarden.
其他題名:	structure, functions and role in human disease /
其他作者:	Wheeler, Deric L.
出版者:	New York, NY :Springer New York : : 2015.,
面頁冊數:	xvii, 440 p. :ill. (some col.), digital ;24 cm.
內容註:	The Eukaryotic Protein Kinase Superfamily -- Evolution of Receptor Tyrosine Kinases -- RTKs in Invertebrates: Lessons in Signal Transduction -- Cell Signaling by Receptor Tyrosine Kinases -- Nuclear Signaling of Receptor Tyrosine Kinases -- Computational and Modeling Aspects of RTK Networks -- Endocytosis of Receptor Tyrosine Kinases -- Structural Features of the Ligand-Binding Extracellular Domain -- Structural Features of the Kinase Domain -- Targeting RTKs in Cancer.-- Mouse Models of Receptor Tyrosine Kinases.
Contained By:	Springer eBooks
標題:	Protein-tyrosine kinase. -
電子資源:	http://dx.doi.org/10.1007/978-1-4939-2053-2
ISBN:	9781493920532 (electronic bk.)

Receptor tyrosine kinases = structure, functions and role in human disease /
Receptor tyrosine kinasesstructure, functions and role in human disease /[electronic resource] :edited by Deric L. Wheeler, Yosef Yarden. - New York, NY :Springer New York :2015. - xvii, 440 p. :ill. (some col.), digital ;24 cm.

The Eukaryotic Protein Kinase Superfamily -- Evolution of Receptor Tyrosine Kinases -- RTKs in Invertebrates: Lessons in Signal Transduction -- Cell Signaling by Receptor Tyrosine Kinases -- Nuclear Signaling of Receptor Tyrosine Kinases -- Computational and Modeling Aspects of RTK Networks -- Endocytosis of Receptor Tyrosine Kinases -- Structural Features of the Ligand-Binding Extracellular Domain -- Structural Features of the Kinase Domain -- Targeting RTKs in Cancer.-- Mouse Models of Receptor Tyrosine Kinases.

Receptor tyrosine kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases, and over the last decade have become the number one targets of cancer drugs. Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease systematically covers, for the first time, the shared structural and functional features of the RTK family. Understanding the evolutionary origin of the 58 RTKs, their roles in invertebrates and in humans, as well as downstream signaling pathways, is essential for fundamental research and for attempts to develop pharmacological agents able to enhance or intercept their actions. The assembly of chapters written by experts underscores commonalities and is an ideal companion volume to The Receptor Tyrosine Kinase Family, which refers to specific subfamilies of RTKs, along with their unique landmarks.

ISBN: 9781493920532 (electronic bk.)

Standard No.: 10.1007/978-1-4939-2053-2doiSubjects--Topical Terms:

737604
Protein-tyrosine kinase.

LC Class. No.: QP606.P78

Dewey Class. No.: 572.6

Receptor tyrosine kinases = structure, functions and role in human disease /
LDR:02386nmm a2200313 a 4500 001 1993322
003 DE-He213
005 20150626155249.0
006 m d
007 cr nn 008maaau
008 151019s2015 nyu s 0 eng d
020 $a 9781493920532 (electronic bk.)
020 $a 9781493920525 (paper)
024 7 $a 10.1007/978-1-4939-2053-2 $2 doi
035 $a 978-1-4939-2053-2
040 $a GP $c GP
041 0 $a eng
050 4 $a QP606.P78
072 7 $a PSF $2 bicssc
072 7 $a SCI049000 $2 bisacsh
082 0 4 $a 572.6 $2 23
090 $a QP606.P78 $b R295 2015
245 0 0 $a Receptor tyrosine kinases $h [electronic resource] : $b structure, functions and role in human disease / $c edited by Deric L. Wheeler, Yosef Yarden.
260 $a New York, NY : $b Springer New York : $b Imprint: Springer, $c 2015.
300 $a xvii, 440 p. : $b ill. (some col.), digital ; $c 24 cm.
505 0 $a The Eukaryotic Protein Kinase Superfamily -- Evolution of Receptor Tyrosine Kinases -- RTKs in Invertebrates: Lessons in Signal Transduction -- Cell Signaling by Receptor Tyrosine Kinases -- Nuclear Signaling of Receptor Tyrosine Kinases -- Computational and Modeling Aspects of RTK Networks -- Endocytosis of Receptor Tyrosine Kinases -- Structural Features of the Ligand-Binding Extracellular Domain -- Structural Features of the Kinase Domain -- Targeting RTKs in Cancer.-- Mouse Models of Receptor Tyrosine Kinases.
520 $a Receptor tyrosine kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases, and over the last decade have become the number one targets of cancer drugs. Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease systematically covers, for the first time, the shared structural and functional features of the RTK family. Understanding the evolutionary origin of the 58 RTKs, their roles in invertebrates and in humans, as well as downstream signaling pathways, is essential for fundamental research and for attempts to develop pharmacological agents able to enhance or intercept their actions. The assembly of chapters written by experts underscores commonalities and is an ideal companion volume to The Receptor Tyrosine Kinase Family, which refers to specific subfamilies of RTKs, along with their unique landmarks.
650 0 $a Protein-tyrosine kinase. $3 737604
650 1 4 $a Life Sciences. $3 890838
650 2 4 $a Cell Biology. $3 892383
650 2 4 $a Receptors. $3 1000988
650 2 4 $a Cancer Research. $3 891172
700 1 $a Wheeler, Deric L. $3 2131490
700 1 $a Yarden, Yosef. $3 2131491
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-1-4939-2053-2
950 $a Biomedical and Life Sciences (Springer-11642)