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The effect of wild blueberry consump...

Bloedon, Taylor K.

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The effect of wild blueberry consumption on the inflammatory response, oxidative stress and DNA damage associated with exercise.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	The effect of wild blueberry consumption on the inflammatory response, oxidative stress and DNA damage associated with exercise./
作者:	Bloedon, Taylor K.
面頁冊數:	154 p.
附註:	Source: Dissertation Abstracts International, Volume: 75-06(E), Section: B.
Contained By:	Dissertation Abstracts International75-06B(E).
標題:	Health Sciences, Nutrition. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3579434
ISBN:	9781303763502

The effect of wild blueberry consumption on the inflammatory response, oxidative stress and DNA damage associated with exercise.
Bloedon, Taylor K.

The effect of wild blueberry consumption on the inflammatory response, oxidative stress and DNA damage associated with exercise. - 154 p.

Source: Dissertation Abstracts International, Volume: 75-06(E), Section: B.

Thesis (Ph.D.)--The University of Maine, 2013.

Strenuous and unfamiliar exercise substantially increases levels of reactive oxygen species (ROS) resulting in significant oxidative stress and elevated inflammation with potential for systemic damage beyond the working muscle. Wild blueberries exhibit both antioxidant and anti-inflammatory properties. This study examined the effect of wild blueberries on the oxidative stress/inflammatory response to exercise in untrained individuals.

ISBN: 9781303763502Subjects--Topical Terms:

1017801
Health Sciences, Nutrition.

The effect of wild blueberry consumption on the inflammatory response, oxidative stress and DNA damage associated with exercise.
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245 1 4 $a The effect of wild blueberry consumption on the inflammatory response, oxidative stress and DNA damage associated with exercise.
300 $a 154 p.
500 $a Source: Dissertation Abstracts International, Volume: 75-06(E), Section: B.
500 $a Adviser: Dorothy Klumis-Zacas.
502 $a Thesis (Ph.D.)--The University of Maine, 2013.
520 $a Strenuous and unfamiliar exercise substantially increases levels of reactive oxygen species (ROS) resulting in significant oxidative stress and elevated inflammation with potential for systemic damage beyond the working muscle. Wild blueberries exhibit both antioxidant and anti-inflammatory properties. This study examined the effect of wild blueberries on the oxidative stress/inflammatory response to exercise in untrained individuals.
520 $a Ten sedentary males (21 -- 26 years of age) completed a single bout of treadmill exercise at 70% of their VO2max before and after consuming 300 g of wild blueberries daily, for eight weeks. Biomarkers for oxidative stress, inflammation and DNA damage; TNFalpha (tumor necrosis factor-alpha), Mn-SOD (manganese-superoxide dismutase), IL-6 (interleukin-6), and DNA damage were measured pre-exercise, and at 0 minutes, 30 minutes, one hour, three hours and six hours post-exercise, before and after wild blueberry consumption.
520 $a A significant increase in IL-6 was observed for time (at 30 minutes and one hour), both pre- and post-exercise, while no significant changes were detected following the intervention. A significant interaction between pre- and post-intervention over time was detected in plasma Mn-SOD concentration. Post hoc comparisons showed no significant differences between time points pre- and post-intervention, although plasma Mn-SOD concentration tended to decrease 30 minutes after exercise with wild blueberry consumption. No significant differences were seen in DNA damage or TNFalpha either with exercise or the intervention.
520 $a This study demonstrates that a single bout of exercise at 70% of VO 2max is sufficient to cause a significant increase in inflammation in untrained individuals as evidenced by plasma levels of IL-6. The small decrease in Mn-SOD concentration after exercise post-intervention indicates a potential benefit of wild blueberries to increase antioxidant capacity and reduce oxidative stress.
590 $a School code: 0113.
650 4 $a Health Sciences, Nutrition. $3 1017801
650 4 $a Health Sciences, General. $3 1017817
650 4 $a Health Sciences, Recreation. $3 1018003
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