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Physiologically-based pharmacokineti...

Peters, Sheila Annie.

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Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Physiologically-based pharmacokinetic (PBPK) modeling and simulations/ Sheila Annie Peters.
其他題名:	principles, methods, and applications in the pharmaceutical industry /
其他題名:	Physiologically based pharmacokinetic modeling and simulations
作者:	Peters, Sheila Annie.
出版者:	Hoboken, N.J. :Wiley, : c2012.,
面頁冊數:	1 online resource (xvii, 430 p.) :ill.
附註:	Wiley online library (ebook collection)
內容註:	Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.
標題:	Pharmacokinetics - Mathematical models. -
電子資源:	http://onlinelibrary.wiley.com/book/10.1002/9781118140291
ISBN:	9781118140291 (electronic bk.)

Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry /
Peters, Sheila Annie.

Physiologically-based pharmacokinetic (PBPK) modeling and simulationsprinciples, methods, and applications in the pharmaceutical industry /[electronic resource] :Physiologically based pharmacokinetic modeling and simulationsSheila Annie Peters. - Hoboken, N.J. :Wiley,c2012. - 1 online resource (xvii, 430 p.) :ill.

Wiley online library (ebook collection)

Includes bibliographical references and index.

Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.

ISBN: 9781118140291 (electronic bk.)

Source: 10.1002/9781118140291Wiley InterSciencehttp://www3.interscience.wiley.comSubjects--Topical Terms:

916739
Pharmacokinetics
--Mathematical models.

LC Class. No.: RM301.5 / .P48 2012eb

Dewey Class. No.: 615/.7

National Library of Medicine Call No.: QV 38

Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry /
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245 1 0 $a Physiologically-based pharmacokinetic (PBPK) modeling and simulations $h [electronic resource] : $b principles, methods, and applications in the pharmaceutical industry / $c Sheila Annie Peters.
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500 $a Wiley online library (ebook collection)
504 $a Includes bibliographical references and index.
505 0 # $a Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.
588 $a Description based on print version record.
650 # 0 $a Pharmacokinetics $x Mathematical models. $3 916739
650 # 0 $a Drugs $x Design $x Mathematical models. $3 768418
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856 4 0 $u http://onlinelibrary.wiley.com/book/10.1002/9781118140291

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Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry / / Peters, Sheila Annie. / Wiley, / 2012	其他

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