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Transcriptional regulation in TATA-l...
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Hsu, Yung-Chun.
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Transcriptional regulation in TATA-less promoters: Role of E2F, Sp1 and promoter features.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Transcriptional regulation in TATA-less promoters: Role of E2F, Sp1 and promoter features./
作者:
Hsu, Yung-Chun.
面頁冊數:
185 p.
附註:
Source: Dissertation Abstracts International, Volume: 64-11, Section: B, page: 5358.
Contained By:
Dissertation Abstracts International64-11B.
標題:
Biology, Molecular. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3113497
Transcriptional regulation in TATA-less promoters: Role of E2F, Sp1 and promoter features.
Hsu, Yung-Chun.
Transcriptional regulation in TATA-less promoters: Role of E2F, Sp1 and promoter features.
- 185 p.
Source: Dissertation Abstracts International, Volume: 64-11, Section: B, page: 5358.
Thesis (Ph.D.)--State University of New York at Buffalo, 2004.
Functional cooperation among transcription factors is a fundamental strategy by which transcription factors regulate promoter activity. Binding sites for both Sp1 and E2F frequently occur in TATA-less promoters in close proximity to one another.Subjects--Topical Terms:
1017719
Biology, Molecular.
Transcriptional regulation in TATA-less promoters: Role of E2F, Sp1 and promoter features.
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Functional cooperation among transcription factors is a fundamental strategy by which transcription factors regulate promoter activity. Binding sites for both Sp1 and E2F frequently occur in TATA-less promoters in close proximity to one another.
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In this study, Sp1 and E2F1 have been found to functionally cooperate with each other in several TATA-less promoters, including dihydrofolate reductase, human DNA polymerase a, mouse thymidylate synthase, and mouse thymidine kinase. Data from th
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In the DNA polymerase a promoter, several regulatory elements in addition to the Sp1 and E2F sites can modulate the activation by Sp1 and/or E2F1. Moreover, data demonstrated that several previously unidentified elements, including a second E2F
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