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Metal-binding properties of the zinc...

Guerrerio, Anthony Lawrence, Jr.

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Metal-binding properties of the zinc fingers in metal responsive element-binding transcription factor-1 and design of single-stranded nucleic acid binding proteins using nucleocapsid-like CCHC zinc-binding domains.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Metal-binding properties of the zinc fingers in metal responsive element-binding transcription factor-1 and design of single-stranded nucleic acid binding proteins using nucleocapsid-like CCHC zinc-binding domains./
Author:	Guerrerio, Anthony Lawrence, Jr.
Description:	90 p.
Notes:	Source: Dissertation Abstracts International, Volume: 64-10, Section: B, page: 4819.
Contained By:	Dissertation Abstracts International64-10B.
Subject:	Biophysics, General. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3107511

Metal-binding properties of the zinc fingers in metal responsive element-binding transcription factor-1 and design of single-stranded nucleic acid binding proteins using nucleocapsid-like CCHC zinc-binding domains.
Guerrerio, Anthony Lawrence, Jr.

Metal-binding properties of the zinc fingers in metal responsive element-binding transcription factor-1 and design of single-stranded nucleic acid binding proteins using nucleocapsid-like CCHC zinc-binding domains. - 90 p.

Source: Dissertation Abstracts International, Volume: 64-10, Section: B, page: 4819.

Thesis (Ph.D.)--The Johns Hopkins University, 2004.

The zinc-induced DNA binding activation of MTF1 was estimated to be half-maximal at a zinc concentration of 2--3 muM. We have measured the metal affinity of each of the six zinc fingers of murine MTF1 in isolation as well as in the context of a Subjects--Topical Terms:

1019105
Biophysics, General.

Metal-binding properties of the zinc fingers in metal responsive element-binding transcription factor-1 and design of single-stranded nucleic acid binding proteins using nucleocapsid-like CCHC zinc-binding domains.
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100 1 $a Guerrerio, Anthony Lawrence, Jr. $3 1950100
245 1 0 $a Metal-binding properties of the zinc fingers in metal responsive element-binding transcription factor-1 and design of single-stranded nucleic acid binding proteins using nucleocapsid-like CCHC zinc-binding domains.
300 $a 90 p.
500 $a Source: Dissertation Abstracts International, Volume: 64-10, Section: B, page: 4819.
500 $a Adviser: Jeremy M. Berg.
502 $a Thesis (Ph.D.)--The Johns Hopkins University, 2004.
520 $a The zinc-induced DNA binding activation of MTF1 was estimated to be half-maximal at a zinc concentration of 2--3 muM. We have measured the metal affinity of each of the six zinc fingers of murine MTF1 in isolation as well as in the context of a
520 $a We have used NC-like CCHC zinc-binding motifs as modules to design single-stranded nucleic acid binding proteins. The affinity for guanine-containing single-stranded oligonucleotides increases with the number of CCHC domains. We show the amino a
590 $a School code: 0098.
650 4 $a Biophysics, General. $3 1019105
650 4 $a Chemistry, Biochemistry. $3 1017722
690 $a 0786
690 $a 0487
710 2 0 $a The Johns Hopkins University. $3 1017431
773 0 $t Dissertation Abstracts International $g 64-10B.
790 1 0 $a Berg, Jeremy M., $e advisor
790 $a 0098
791 $a Ph.D.
792 $a 2004
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3107511