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In vitro quantification of mitral re...

Zhang, Haosen.

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In vitro quantification of mitral regurgitant flow with fast MRI.

Record Type:	Electronic resources : Monograph/item
Title/Author:	In vitro quantification of mitral regurgitant flow with fast MRI./
Author:	Zhang, Haosen.
Description:	301 p.
Notes:	Source: Dissertation Abstracts International, Volume: 64-07, Section: B, page: 3390.
Contained By:	Dissertation Abstracts International64-07B.
Subject:	Engineering, Biomedical. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3098214

In vitro quantification of mitral regurgitant flow with fast MRI.
Zhang, Haosen.

In vitro quantification of mitral regurgitant flow with fast MRI. - 301 p.

Source: Dissertation Abstracts International, Volume: 64-07, Section: B, page: 3390.

Thesis (Ph.D.)--Cleveland State University, 2003.

Reliable diagnosis of mitral valve regurgitation is important for proper patient treatment. However, due to the physiologic and functional complications, quantification of the regurgitant flow volume is still a problem in Cardiology.Subjects--Topical Terms:

1017684
Engineering, Biomedical.

In vitro quantification of mitral regurgitant flow with fast MRI.
LDR:02867nmm 2200301 4500 001 1857607
005 20040816072816.5
008 130614s2003 eng d
035 $a (UnM)AAI3098214
035 $a AAI3098214
040 $a UnM $c UnM
100 1 $a Zhang, Haosen. $3 1945323
245 1 0 $a In vitro quantification of mitral regurgitant flow with fast MRI.
300 $a 301 p.
500 $a Source: Dissertation Abstracts International, Volume: 64-07, Section: B, page: 3390.
500 $a Adviser: George P. Chatzimavroudis.
502 $a Thesis (Ph.D.)--Cleveland State University, 2003.
520 $a Reliable diagnosis of mitral valve regurgitation is important for proper patient treatment. However, due to the physiologic and functional complications, quantification of the regurgitant flow volume is still a problem in Cardiology.
520 $a Magnetic resonance phase velocity mapping (MRPVM) is the only clinic technique capable of measuring three-directional velocity components in a single slice. With the development of <italic>k-space</italic> segmented MRPVM, the image acquisition time can be dramatically reduced. This study consisted of two phases. In the first phase, segmented MRPVM was evaluated <italic> in vitro</italic> in straight tubes, under steady and pulsatile flow conditions, and clinically in the aorta of 20 human subjects. The results showed that segmented MRPVM can provide accurate velocity and flow rate measurements both <italic> in vitro</italic> (errors <5% for the through-plane and the in-plane measurements) and clinically (less than 2% difference between segmented and non-segmented MRPVM).
520 $a Based on these results, the second phase of the study evaluated segmented MRPVM in quantifying the regurgitant flow through mitral valve models using a new <italic>control volume</italic> (<italic>CV</italic>) <italic> method</italic>, under steady and pulsatile flow conditions <italic>in vitro </italic>. The results showed a close agreement (errors <10%) between segmented and non-segmented MRPVM-measured regurgitant flow rates (and flow volumes) and the actual flow rates (and the actual flow volumes), regardless of the valve model geometry and the presence of the aortic outflow. The size of the <italic> control volume</italic> should be selected carefully in order to exclude the region of flow acceleration and velocity aliasing. In conclusion, the <italic> CV method</italic> using the <italic>k-space</italic> segmented MRPVM demonstrates great clinical potential in quantifying the mitral regurgitant flow.
590 $a School code: 0466.
650 4 $a Engineering, Biomedical. $3 1017684
650 4 $a Biophysics, Medical. $3 1017681
650 4 $a Health Sciences, Radiology. $3 1019076
690 $a 0541
690 $a 0760
690 $a 0574
710 2 0 $a Cleveland State University. $3 1020754
773 0 $t Dissertation Abstracts International $g 64-07B.
790 1 0 $a Chatzimavroudis, George P., $e advisor
790 $a 0466
791 $a Ph.D.
792 $a 2003
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3098214