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Computational modeling and simulatio...

Hu, Zhenhua.

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Computational modeling and simulation of heart ventricular mechanics from tagged MRI.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Computational modeling and simulation of heart ventricular mechanics from tagged MRI./
Author:	Hu, Zhenhua.
Description:	127 p.
Notes:	Source: Dissertation Abstracts International, Volume: 66-02, Section: B, page: 0985.
Contained By:	Dissertation Abstracts International66-02B.
Subject:	Computer Science. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3165697
ISBN:	054200593X

Computational modeling and simulation of heart ventricular mechanics from tagged MRI.
Hu, Zhenhua.

Computational modeling and simulation of heart ventricular mechanics from tagged MRI. - 127 p.

Source: Dissertation Abstracts International, Volume: 66-02, Section: B, page: 0985.

Thesis (Ph.D.)--University of Pennsylvania, 2005.

Heart ventricular mechanics has been investigated intensively in the last four decades. The passive material properties, the ventricular geometry and muscular architecture, and the myocardial activation are among the most important determinants of cardiac mechanics. The heart muscle is anisotropic, inhomogeneous, and highly nonlinear. The heart ventricular geometry is irregular and object dependent. The muscular architecture includes the organization of the fiber and the connective tissues. Studies of the myocardial activation have been carried out at both cell and tissue levels.

ISBN: 054200593XSubjects--Topical Terms:

626642
Computer Science.

Computational modeling and simulation of heart ventricular mechanics from tagged MRI.
LDR:02185nmm 2200313 4500 001 1850922
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035 $a AAI3165697
040 $a UnM $c UnM
100 1 $a Hu, Zhenhua. $3 1938827
245 1 0 $a Computational modeling and simulation of heart ventricular mechanics from tagged MRI.
300 $a 127 p.
500 $a Source: Dissertation Abstracts International, Volume: 66-02, Section: B, page: 0985.
500 $a Supervisors: Dimitris N. Metaxas; Leon Axel.
502 $a Thesis (Ph.D.)--University of Pennsylvania, 2005.
520 $a Heart ventricular mechanics has been investigated intensively in the last four decades. The passive material properties, the ventricular geometry and muscular architecture, and the myocardial activation are among the most important determinants of cardiac mechanics. The heart muscle is anisotropic, inhomogeneous, and highly nonlinear. The heart ventricular geometry is irregular and object dependent. The muscular architecture includes the organization of the fiber and the connective tissues. Studies of the myocardial activation have been carried out at both cell and tissue levels.
520 $a Previous work from our research group has successfully estimated the in-vivo motion and deformation of both the left and the right ventricles. In this dissertation, we first present a model to optimize the fiber and sheet orientation. Then, we present a stochastic model to estimate the in-vivo myocardium material properties, the active forces generated along fiber orientation, and stress distribution in both ventricles. Using the model, we have simulated the mechanical events of a few different heart diseases. Noticeable strain and stress differences are found between normal and diseased hearts.
590 $a School code: 0175.
650 4 $a Computer Science. $3 626642
650 4 $a Biophysics, Medical. $3 1017681
650 4 $a Engineering, Biomedical. $3 1017684
690 $a 0984
690 $a 0760
690 $a 0541
710 2 0 $a University of Pennsylvania. $3 1017401
773 0 $t Dissertation Abstracts International $g 66-02B.
790 1 0 $a Metaxas, Dimitris N., $e advisor
790 1 0 $a Axel, Leon, $e advisor
790 $a 0175
791 $a Ph.D.
792 $a 2005
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3165697