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Effect of vitamin C upon the acute s...

Johnson, Robyn D.

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Effect of vitamin C upon the acute stress response.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Effect of vitamin C upon the acute stress response./
Author:	Johnson, Robyn D.
Description:	68 p.
Notes:	Source: Masters Abstracts International, Volume: 42-01, page: 0146.
Contained By:	Masters Abstracts International42-01.
Subject:	Biology, Animal Physiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1415163
ISBN:	0496199501

Effect of vitamin C upon the acute stress response.
Johnson, Robyn D.

Effect of vitamin C upon the acute stress response. - 68 p.

Source: Masters Abstracts International, Volume: 42-01, page: 0146.

Thesis (M.S.)--The University of Alabama in Huntsville, 2003.

This laboratory previously reported that 200 mg vitamin C/day supplementation to Sprague-Dawley rats significantly reduced the adrenal cortex response to chronic immobilization stress. This study extends that research to investigate the effect of the same three-week feeding of vitamin C by oral gavage upon the acute stress response to intraperitoneal injection of cold, hypertonic saline. Stress had statistically significant (p < 0.05) effects on adrenal ascorbic acid (AAA) depletion, hypothalamic CRH and blood levels of ACTH and corticosterone. Vitamin C treatment had a modulating effect upon these parameters, though not statistically significant. The composite pattern of increased hypothalamic CRH, reduced depletion of AAA and lowered stress levels of blood ACTH and corticosterone under vitamin C feeding is consistent with a negative modulation of the acute stress response. In vitro incubation of adrenal glands from vitamin C-treated animals suggests that vitamin C may slightly reduce the responsivity of the gland to ACTH.

ISBN: 0496199501Subjects--Topical Terms:

1017835
Biology, Animal Physiology.

Effect of vitamin C upon the acute stress response.
LDR:01898nmm 2200277 4500 001 1843106
005 20051010101600.5
008 130614s2003 eng d
020 $a 0496199501
035 $a (UnM)AAI1415163
035 $a AAI1415163
040 $a UnM $c UnM
100 1 $a Johnson, Robyn D. $3 1931349
245 1 0 $a Effect of vitamin C upon the acute stress response.
300 $a 68 p.
500 $a Source: Masters Abstracts International, Volume: 42-01, page: 0146.
500 $a Chair: P. Samuel Campbell.
502 $a Thesis (M.S.)--The University of Alabama in Huntsville, 2003.
520 $a This laboratory previously reported that 200 mg vitamin C/day supplementation to Sprague-Dawley rats significantly reduced the adrenal cortex response to chronic immobilization stress. This study extends that research to investigate the effect of the same three-week feeding of vitamin C by oral gavage upon the acute stress response to intraperitoneal injection of cold, hypertonic saline. Stress had statistically significant (p < 0.05) effects on adrenal ascorbic acid (AAA) depletion, hypothalamic CRH and blood levels of ACTH and corticosterone. Vitamin C treatment had a modulating effect upon these parameters, though not statistically significant. The composite pattern of increased hypothalamic CRH, reduced depletion of AAA and lowered stress levels of blood ACTH and corticosterone under vitamin C feeding is consistent with a negative modulation of the acute stress response. In vitro incubation of adrenal glands from vitamin C-treated animals suggests that vitamin C may slightly reduce the responsivity of the gland to ACTH.
590 $a School code: 0278.
650 4 $a Biology, Animal Physiology. $3 1017835
650 4 $a Health Sciences, Nutrition. $3 1017801
690 $a 0433
690 $a 0570
710 2 0 $a The University of Alabama in Huntsville. $3 1017884
773 0 $t Masters Abstracts International $g 42-01.
790 1 0 $a Campbell, P. Samuel, $e advisor
790 $a 0278
791 $a M.S.
792 $a 2003
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1415163