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Statistical design and analysis of h...
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Remlinger, Katja S.
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Statistical design and analysis of high throughput screening data using pooling experiments and data mining techniques.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Statistical design and analysis of high throughput screening data using pooling experiments and data mining techniques./
作者:
Remlinger, Katja S.
面頁冊數:
241 p.
附註:
Source: Dissertation Abstracts International, Volume: 65-04, Section: B, page: 1942.
Contained By:
Dissertation Abstracts International65-04B.
標題:
Statistics. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3128784
ISBN:
0496760461
Statistical design and analysis of high throughput screening data using pooling experiments and data mining techniques.
Remlinger, Katja S.
Statistical design and analysis of high throughput screening data using pooling experiments and data mining techniques.
- 241 p.
Source: Dissertation Abstracts International, Volume: 65-04, Section: B, page: 1942.
Thesis (Ph.D.)--North Carolina State University, 2004.
Discovery of a new drug involves screening large chemical libraries to identify new and diverse active compounds. Only a very small percentage of the compounds in the library are active. Naive screening approaches of testing all compounds in the
ISBN: 0496760461Subjects--Topical Terms:
517247
Statistics.
Statistical design and analysis of high throughput screening data using pooling experiments and data mining techniques.
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This work investigates pooling experiments as one possible approach of improving screening efficiency and gaining insight into the structure-activity relationships. Four different pooling designs are proposed using two design criteria, optimal c
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