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The isolation, fractionation, and pu...

Gurfinkel, Debbie M.

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The isolation, fractionation, and purification of soyasaponins and the evaluation of their colon anti-carcinogenic activity.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The isolation, fractionation, and purification of soyasaponins and the evaluation of their colon anti-carcinogenic activity./
作者:	Gurfinkel, Debbie M.
面頁冊數:	227 p.
附註:	Source: Dissertation Abstracts International, Volume: 65-05, Section: B, page: 2350.
Contained By:	Dissertation Abstracts International65-05B.
標題:	Health Sciences, Nutrition. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=NQ91634
ISBN:	0612916340

The isolation, fractionation, and purification of soyasaponins and the evaluation of their colon anti-carcinogenic activity.
Gurfinkel, Debbie M.

The isolation, fractionation, and purification of soyasaponins and the evaluation of their colon anti-carcinogenic activity. - 227 p.

Source: Dissertation Abstracts International, Volume: 65-05, Section: B, page: 2350.

Thesis (Ph.D.)--University of Toronto (Canada), 2004.

Saponins are bioactive compounds found in many plant materials, including legumes. The objectives of the present work were to isolate, fractionate, and purify saponins from soybeans, known as soyasaponins; to determine their potential in vitro c

ISBN: 0612916340Subjects--Topical Terms:

1017801
Health Sciences, Nutrition.

The isolation, fractionation, and purification of soyasaponins and the evaluation of their colon anti-carcinogenic activity.
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245 1 4 $a The isolation, fractionation, and purification of soyasaponins and the evaluation of their colon anti-carcinogenic activity.
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500 $a Adviser: A. V. Rao.
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520 $a Saponins are bioactive compounds found in many plant materials, including legumes. The objectives of the present work were to isolate, fractionate, and purify saponins from soybeans, known as soyasaponins; to determine their potential in vitro c
520 $a Because of the absence of commercially available purified soyasaponins, researchers have always had to isolate the soyasaponins themselves, limiting research on their bioactivity. The methods developed here exploited simple and inexpensive techn
520 $a To investigate the role of colonic microflora, soyasaponins were incubated under anaerobic conditions with human microflora. The soyasaponins were converted to soyasapogenol A and soyasapogenol B.
520 $a The purified soyasaponins were tested for their ability to suppress the growth of HT-29 colon cancer cells. The most potent compounds were the aglycones, soyasapogenol A and B, which demonstrated a dose dependent and statistically significant su
590 $a School code: 0779.
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650 4 $a Health Sciences, Oncology. $3 1018566
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