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Nanomechanical and nanostructural pr...

Grau Marrero, Nayra.

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Nanomechanical and nanostructural properties of synostosed cranial sutures.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Nanomechanical and nanostructural properties of synostosed cranial sutures./
作者:	Grau Marrero, Nayra.
面頁冊數:	61 p.
附註:	Source: Masters Abstracts International, Volume: 42-05, page: 1645.
Contained By:	Masters Abstracts International42-05.
標題:	Biophysics, Medical. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1418616
ISBN:	0496233895

Nanomechanical and nanostructural properties of synostosed cranial sutures.
Grau Marrero, Nayra.

Nanomechanical and nanostructural properties of synostosed cranial sutures. - 61 p.

Source: Masters Abstracts International, Volume: 42-05, page: 1645.

Thesis (M.S.)--University of Illinois at Chicago, 2004.

Craniosynostosis is the premature closure of one or more cranial sutures. Suture closure or synostosis of pathological sutures has rarely been studied. Recent advances in nanotechnology allow determining the properties of cranial sutures at a nanoscale level. A total of ten synostosed sutures, five sagittal and five metopic were scanned in both the endocranial and ectocranial surfaces with the use of an Atomic Force Microscope. The nanomechanical properties or Young's modulus (E) and the nanostructural properties or Surface Roughness (Ra) were obtained and analyzed statistically using Two-way analysis of variance. The topographic images indicated robust variations in sutural surface with randomly localized peaks and valleys. Analysis of surface roughness within 5 x 5 micron scan sizes revealed that the metopic suture had a significantly greater Ra (223.6 +/- 93.3 nm) than the sagittal suture (142.9 +/- 90.3 nm) (p < 0.01). There were also statistically significant (p < 0.01) differences in the Young's modulus. The E of the sagittal suture at 0.7 +/- 0.2 Mpa was significantly higher than the metopic suture at 0.5 +/- 0.1 Mpa respectively. The present findings indicate substantial variations in both the nanomechanical and nanostructural properties between sagittal and metopic sutures, suggesting different mechanisms in suture fusion or synostosis.

ISBN: 0496233895Subjects--Topical Terms:

1017681
Biophysics, Medical.

Nanomechanical and nanostructural properties of synostosed cranial sutures.
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300 $a 61 p.
500 $a Source: Masters Abstracts International, Volume: 42-05, page: 1645.
500 $a Adviser: Jeremy Mao.
502 $a Thesis (M.S.)--University of Illinois at Chicago, 2004.
520 $a Craniosynostosis is the premature closure of one or more cranial sutures. Suture closure or synostosis of pathological sutures has rarely been studied. Recent advances in nanotechnology allow determining the properties of cranial sutures at a nanoscale level. A total of ten synostosed sutures, five sagittal and five metopic were scanned in both the endocranial and ectocranial surfaces with the use of an Atomic Force Microscope. The nanomechanical properties or Young's modulus (E) and the nanostructural properties or Surface Roughness (Ra) were obtained and analyzed statistically using Two-way analysis of variance. The topographic images indicated robust variations in sutural surface with randomly localized peaks and valleys. Analysis of surface roughness within 5 x 5 micron scan sizes revealed that the metopic suture had a significantly greater Ra (223.6 +/- 93.3 nm) than the sagittal suture (142.9 +/- 90.3 nm) (p < 0.01). There were also statistically significant (p < 0.01) differences in the Young's modulus. The E of the sagittal suture at 0.7 +/- 0.2 Mpa was significantly higher than the metopic suture at 0.5 +/- 0.1 Mpa respectively. The present findings indicate substantial variations in both the nanomechanical and nanostructural properties between sagittal and metopic sutures, suggesting different mechanisms in suture fusion or synostosis.
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