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Phylogenetic and ecological investig...

Mincer, Tracy John.

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Phylogenetic and ecological investigations of secondary metabolite producing marine bacteria and their potential for biotechnology.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Phylogenetic and ecological investigations of secondary metabolite producing marine bacteria and their potential for biotechnology./
作者:	Mincer, Tracy John.
面頁冊數:	134 p.
附註:	Source: Dissertation Abstracts International, Volume: 65-08, Section: B, page: 3900.
Contained By:	Dissertation Abstracts International65-08B.
標題:	Biology, Oceanography. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3142452
ISBN:	0496001701

Phylogenetic and ecological investigations of secondary metabolite producing marine bacteria and their potential for biotechnology.
Mincer, Tracy John.

Phylogenetic and ecological investigations of secondary metabolite producing marine bacteria and their potential for biotechnology. - 134 p.

Source: Dissertation Abstracts International, Volume: 65-08, Section: B, page: 3900.

Thesis (Ph.D.)--University of California, San Diego, 2004.

The goal of this research was to investigate bacteria from the marine environment using molecular phylogenetic methods in combination with classical microbiology and selective isolation techniques in order to determine their evolutionary relationships, distributions, and potential ecological functions. A majority of this work focused upon bacteria of the Order Actinomycetales (actinomycetes) however a genus of Gram-negative bacteria, Saprospira , was investigated as well. Interfacing with the chemistry program in our laboratory many of the phylogenetically novel bacteria were investigated with regards to their ability to produce novel secondary metabolites.

ISBN: 0496001701Subjects--Topical Terms:

783691
Biology, Oceanography.

Phylogenetic and ecological investigations of secondary metabolite producing marine bacteria and their potential for biotechnology.
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245 1 0 $a Phylogenetic and ecological investigations of secondary metabolite producing marine bacteria and their potential for biotechnology.
300 $a 134 p.
500 $a Source: Dissertation Abstracts International, Volume: 65-08, Section: B, page: 3900.
500 $a Chair: William H. Fenical.
502 $a Thesis (Ph.D.)--University of California, San Diego, 2004.
520 $a The goal of this research was to investigate bacteria from the marine environment using molecular phylogenetic methods in combination with classical microbiology and selective isolation techniques in order to determine their evolutionary relationships, distributions, and potential ecological functions. A majority of this work focused upon bacteria of the Order Actinomycetales (actinomycetes) however a genus of Gram-negative bacteria, Saprospira , was investigated as well. Interfacing with the chemistry program in our laboratory many of the phylogenetically novel bacteria were investigated with regards to their ability to produce novel secondary metabolites.
520 $a Chapter I of this thesis serves as an introduction to the work performed and discuss the unifying themes of secondary metabolite production and prokaryotic diversity. Chapter II presents the first study of this thesis work describing marine adaptations and bioactivity of fermentation extracts from a new taxon of actinomycete, "Salinospora" gen. nov. Chapter III further investigates "Salinospora" in the marine sediment environment using selective isolation and cultivation-independent techniques. Chapter IV introduces another marine adapted actinomycete group with the proposed name "Marinophilus" gen. nov. Chapter V presents an investigation of the phylogenetic distribution and diterpenoid production among members of the Gram-negative bacterial genus Saprospira . Appendix A is a reprint of the manuscript describing the first bioactive molecule discovered from "Salinospora". Appendix B is a summary of a U.S. patent application for the use of " Salinospora" as a specific platform technology in drug-discovery and biotechnology. Appendix B is also a summary of the U.S. patent application for the use of "Marinophilus" as a specific platform technology in drug-discovery and biotechnology.
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650 4 $a Biology, Microbiology. $3 1017734
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