東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Effects of high salt intake on endot...

Bratcher, Adrienne Patrece.

FindBook

Google Book

Amazon

博客來

Effects of high salt intake on endothelial-mediated dilation and construction in the vasculature.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Effects of high salt intake on endothelial-mediated dilation and construction in the vasculature./
作者:	Bratcher, Adrienne Patrece.
面頁冊數:	110 p.
附註:	Source: Dissertation Abstracts International, Volume: 68-05, Section: B, page: 2868.
Contained By:	Dissertation Abstracts International68-05B.
標題:	Biology, Animal Physiology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3267076
ISBN:	9780549051589

Effects of high salt intake on endothelial-mediated dilation and construction in the vasculature.
Bratcher, Adrienne Patrece.

Effects of high salt intake on endothelial-mediated dilation and construction in the vasculature. - 110 p.

Source: Dissertation Abstracts International, Volume: 68-05, Section: B, page: 2868.

Thesis (Ph.D.)--University of Louisville, 2007.

Hypertension is a major health problem in the United States, where more than 50 million people (1 in 4 adults) have the condition. Hypertension is commonly associated with a narrowing of the arteries, which causes high blood pressure. High dietary salt intake has been shown to contribute to the development of hypertension in the DOCA-salt model. However, elevations in salt intake alone may cause significant changes in the microvessel response to vasoactive drugs. Therefore, this dissertation is focused on the determination that increased dietary salt intake alone will have a major effect on the sensitivity of microvessels/macrovessels exposed to various vasoactive agents. Our data suggest that the dilator and contrictor responses in the microvasculature are decreased. However, there appears to only be an increase in constrictor response and similar decrease in dilator response in the macrovasculature. Thus, impairment of the arteriolar and aortic responses due to increased dietary conditions could predispose rats to the development of hypertension. Our data also demonstrate that these alterations could be due to an increase in oxidative stress.

ISBN: 9780549051589Subjects--Topical Terms:

1017835
Biology, Animal Physiology.

Effects of high salt intake on endothelial-mediated dilation and construction in the vasculature.
LDR:02097nmm 2200289 4500 001 1835713
005 20071226140438.5
008 130610s2007 eng d
020 $a 9780549051589
035 $a (UMI)AAI3267076
035 $a AAI3267076
040 $a UMI $c UMI
100 1 $a Bratcher, Adrienne Patrece. $3 1924336
245 1 0 $a Effects of high salt intake on endothelial-mediated dilation and construction in the vasculature.
300 $a 110 p.
500 $a Source: Dissertation Abstracts International, Volume: 68-05, Section: B, page: 2868.
500 $a Adviser: Irving G. Joshua.
502 $a Thesis (Ph.D.)--University of Louisville, 2007.
520 $a Hypertension is a major health problem in the United States, where more than 50 million people (1 in 4 adults) have the condition. Hypertension is commonly associated with a narrowing of the arteries, which causes high blood pressure. High dietary salt intake has been shown to contribute to the development of hypertension in the DOCA-salt model. However, elevations in salt intake alone may cause significant changes in the microvessel response to vasoactive drugs. Therefore, this dissertation is focused on the determination that increased dietary salt intake alone will have a major effect on the sensitivity of microvessels/macrovessels exposed to various vasoactive agents. Our data suggest that the dilator and contrictor responses in the microvasculature are decreased. However, there appears to only be an increase in constrictor response and similar decrease in dilator response in the macrovasculature. Thus, impairment of the arteriolar and aortic responses due to increased dietary conditions could predispose rats to the development of hypertension. Our data also demonstrate that these alterations could be due to an increase in oxidative stress.
590 $a School code: 0110.
650 4 $a Biology, Animal Physiology. $3 1017835
650 4 $a Health Sciences, Public Health. $3 1017659
650 4 $a Biology, Physiology. $3 1017816
690 $a 0433
690 $a 0573
690 $a 0719
710 2 0 $a University of Louisville. $3 1017614
773 0 $t Dissertation Abstracts International $g 68-05B.
790 1 0 $a Joshua, Irving G., $e advisor
790 $a 0110
791 $a Ph.D.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3267076