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Functional neuroimaging investigatio...

Prince, Steven Eric.

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Functional neuroimaging investigations of human memory: Comparisons of successful encoding and retrieval for relational and item information.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Functional neuroimaging investigations of human memory: Comparisons of successful encoding and retrieval for relational and item information./
作者:	Prince, Steven Eric.
面頁冊數:	180 p.
附註:	Source: Dissertation Abstracts International, Volume: 68-03, Section: B, page: 1955.
Contained By:	Dissertation Abstracts International68-03B.
標題:	Biology, Neuroscience. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3255598

Functional neuroimaging investigations of human memory: Comparisons of successful encoding and retrieval for relational and item information.
Prince, Steven Eric.

Functional neuroimaging investigations of human memory: Comparisons of successful encoding and retrieval for relational and item information. - 180 p.

Source: Dissertation Abstracts International, Volume: 68-03, Section: B, page: 1955.

Thesis (Ph.D.)--Duke University, 2007.

Memory is a complex and multifaceted entity. Cognitive psychology has adopted terminology to help simplify the study of memory. For example, one can consider the cognitive process the brain is engaged in, such as encoding versus retrieval. Similarly, one can consider the content of information, such as words, faces, or scenes. Content and process can also interact such as with instructions to view a face that happens to be situated next to a house (item memory) versus instructions to evaluate whether the face 'belongs' in the house (relational memory). Although neuropsychology, animal lesion studies, and cognitive neuroscience have identified brain structures that are consistently associated with memory performance, such as the medial temporal lobes (MTL) and prefrontal cortex (PFC), the specifics of when and why such regions participate in memory is still largely unexplored. Theoretical standpoints are often at odds about whether regions such as the MTL operate as a functional unit, supporting memory in general, or whether subregions within the MTL support specific types of memory (e.g. item versus relational memory). To investigate how memory processes might recruit unique and common brain regions, three functional magnetic resonance imaging (fMRI) studies were conducted. Each study involved comparisons of successful encoding (trials later remembered versus forgotten) and successful retrieval (hits versus misses). Experiment 1, using semantic and perceptual word pairs, found unique contributions for subregions in the MTL and PFC, dependent on memory phase and stimulus class. One region in the left hippocampus was associated with memory success, regardless of either memory phase or stimulus class. Experiment 2, using faces and scenes, found unique contributions for 'stimulus sensitive' subregions of the fusiform gyrus and parahippocampal gyrus, as well as for the PFC, and MTL that were dependent on content-process interactions, or independent of content and process. Experiment 3, using faces, scenes, and face-scene pairings, found unique contributions for subregions of the MTL and PFC based on item versus relational processing and memory phase. Together, the results of the three experiments provide support for dichotomies in brain structures based on specific processes, specific content, or process-content interactions.Subjects--Topical Terms:

1017680
Biology, Neuroscience.

Functional neuroimaging investigations of human memory: Comparisons of successful encoding and retrieval for relational and item information.
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