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Small scale contact and adhesion of ...

Cao, Yifang.

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Small scale contact and adhesion of soft materials in nano- and bio-systems.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Small scale contact and adhesion of soft materials in nano- and bio-systems./
作者:	Cao, Yifang.
面頁冊數:	205 p.
附註:	Source: Dissertation Abstracts International, Volume: 67-04, Section: B, page: 2186.
Contained By:	Dissertation Abstracts International67-04B.
標題:	Applied Mechanics. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3214555
ISBN:	9780542647857

Small scale contact and adhesion of soft materials in nano- and bio-systems.
Cao, Yifang.

Small scale contact and adhesion of soft materials in nano- and bio-systems. - 205 p.

Source: Dissertation Abstracts International, Volume: 67-04, Section: B, page: 2186.

Thesis (Ph.D.)--Princeton University, 2006.

This dissertation presents the results obtained from recent experimental, theoretical and computational studies of small scale contact and adhesion of soft materials in both the nano- and bio-systems. These include: stamped flexible/organic electronic devices, and polydimethylsiloxane (PDMS) and biological human osteoscarcoma (HOS) cells. Following a presentation of a method for determining the initial contact point and nanoindentation load-indentation depth characteristics for soft materials, adhesion and contact-induced phenomena are discussed for the processing of organic electronics structures. These include experiments and models that provide new insights into metallic electrode cold welding and organic material pattern transfer processes that are being explored for the fabrication of small organic structures that are relevant to flexible bioelectronics and bioMEMS. Subsequently, a shear assay technique and cell spreading study are presented for the characterization of cell viscoelastic properties and cell prestress. These then present new evidence of how contact guidance (alignment of cells) occurs along microgrooved PDMS structures that have the potential to reduce the overall levels of scar tissue formation. The implications of the results are also assessed for cell biophysics, and potential applications in flexible bioMEMS structures.

ISBN: 9780542647857Subjects--Topical Terms:

1018410
Applied Mechanics.

Small scale contact and adhesion of soft materials in nano- and bio-systems.
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500 $a Adviser: Winston O. Soboyejo.
502 $a Thesis (Ph.D.)--Princeton University, 2006.
520 $a This dissertation presents the results obtained from recent experimental, theoretical and computational studies of small scale contact and adhesion of soft materials in both the nano- and bio-systems. These include: stamped flexible/organic electronic devices, and polydimethylsiloxane (PDMS) and biological human osteoscarcoma (HOS) cells. Following a presentation of a method for determining the initial contact point and nanoindentation load-indentation depth characteristics for soft materials, adhesion and contact-induced phenomena are discussed for the processing of organic electronics structures. These include experiments and models that provide new insights into metallic electrode cold welding and organic material pattern transfer processes that are being explored for the fabrication of small organic structures that are relevant to flexible bioelectronics and bioMEMS. Subsequently, a shear assay technique and cell spreading study are presented for the characterization of cell viscoelastic properties and cell prestress. These then present new evidence of how contact guidance (alignment of cells) occurs along microgrooved PDMS structures that have the potential to reduce the overall levels of scar tissue formation. The implications of the results are also assessed for cell biophysics, and potential applications in flexible bioMEMS structures.
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