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Magnetic resonance imaging of circul...
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DiCarlo, Julie Camille.
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Magnetic resonance imaging of circulation.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Magnetic resonance imaging of circulation./
作者:
DiCarlo, Julie Camille.
面頁冊數:
144 p.
附註:
Source: Dissertation Abstracts International, Volume: 67-03, Section: B, page: 1597.
Contained By:
Dissertation Abstracts International67-03B.
標題:
Engineering, Biomedical. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3208996
ISBN:
9780542571091
Magnetic resonance imaging of circulation.
DiCarlo, Julie Camille.
Magnetic resonance imaging of circulation.
- 144 p.
Source: Dissertation Abstracts International, Volume: 67-03, Section: B, page: 1597.
Thesis (Ph.D.)--Stanford University, 2006.
Velocity measurements have wide use in the diagnosis of cardiovascular disease. In the largest vessels, velocity pressure gradients are used to diagnose stenosis and coarctation. Doppler ultrasound (US) is currently used, but suffers from positioning difficulties, and is unable to depict coronary structure or evaluate pericardial function. Magnetic resonance (MR) imaging can perform these functions and is a compelling modality to provide useful information beyond the capabilities of US. The addition of a tool that is the MR equivalent of Doppler US could revolutionize patient examination and monitoring. The ability to image flow at the other extreme, in the smallest vessels, is important in determining the mechanisms of peripheral vascular disease, which remain largely unknown. Physicians are reluctant to perform tissue biopsy because of wound healing concerns. MR examination when neuropathy first presents would help in determining and tracking the proper treatment course, improving patient prognosis.
ISBN: 9780542571091Subjects--Topical Terms:
1017684
Engineering, Biomedical.
Magnetic resonance imaging of circulation.
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Velocity measurements have wide use in the diagnosis of cardiovascular disease. In the largest vessels, velocity pressure gradients are used to diagnose stenosis and coarctation. Doppler ultrasound (US) is currently used, but suffers from positioning difficulties, and is unable to depict coronary structure or evaluate pericardial function. Magnetic resonance (MR) imaging can perform these functions and is a compelling modality to provide useful information beyond the capabilities of US. The addition of a tool that is the MR equivalent of Doppler US could revolutionize patient examination and monitoring. The ability to image flow at the other extreme, in the smallest vessels, is important in determining the mechanisms of peripheral vascular disease, which remain largely unknown. Physicians are reluctant to perform tissue biopsy because of wound healing concerns. MR examination when neuropathy first presents would help in determining and tracking the proper treatment course, improving patient prognosis.
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Velocity measurement in large vessels can be performed by MR phase contrast. However, phase contrast measures voxel average velocity, resulting in partial volume averaging errors. Fourier velocity encoding (FVE) enables full velocity spectra measurement. The application of variable-density sampling trajectories to FVE improves velocity detection without significant increases in readout time or aliasing artifact. Results in phantoms and volunteers confirm that variable-density acquisition improves resolution and FOV, with the greatest impact on range improvement to allow unambiguous imaging of jets.
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Imaging at the capillary level presents a different set of challenges, including the need for better than conventional spatial resolution and the simultaneous need for fast acquisition of 3D data sets that enable contrast-based techniques. Small surface receive coils were designed to provide the best possible hardware SNR for skin vessel imaging. Investigation of the coil noise reduction from cooling with liquid nitrogen shows that SNR gains are outweighed by B1 falloff losses due to cryostat separation at the smallest coil size. Cooling gains are further limited by tuning element losses. The optimized coil was used to acquire skin images with 78-micron in-plane resolution. Targeted receive coils also provide SNR gains that enable diagnostic imaging of laryngeal cancer and cochlea morphological modeling.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3208996
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