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Influence of vitamin D receptor gene...
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Harne, Amanda Janel.
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Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training./
作者:
Harne, Amanda Janel.
面頁冊數:
97 p.
附註:
Source: Masters Abstracts International, Volume: 43-03, page: 0776.
Contained By:
Masters Abstracts International43-03.
標題:
Biology, Genetics. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1423947
ISBN:
9780496128396
Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training.
Harne, Amanda Janel.
Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training.
- 97 p.
Source: Masters Abstracts International, Volume: 43-03, page: 0776.
Thesis (M.A.)--University of Maryland, College Park, 2005.
The purpose of the study was to examine the influence of the FokI and BsmI polymorphisms of the vitamin D receptor gene on changes in insulin sensitivity with aerobic exercise training in men and women at increased risk for type 2 diabetes mellitus (T2DM). Subjects were genotyped and underwent oral glucose tolerance tests before and after six months of training. Due to mis-genotyping of the BsmI polymorphism, results for that variant were not reported. There were no significant differences between FokI genotype groups in insulin sensitivity before or after training. However, among subjects who completed training, FF homozygotes had significantly higher baseline fasting glucose and insulin levels than f allele carriers. While the FokI polymorphism does not appear to mediate training-induced changes in indices of glucose and insulin metabolism, it may influence fasting glucose and insulin levels and the development of insulin resistance in individuals at increased risk for T2DM.
ISBN: 9780496128396Subjects--Topical Terms:
1017730
Biology, Genetics.
Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training.
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The purpose of the study was to examine the influence of the FokI and BsmI polymorphisms of the vitamin D receptor gene on changes in insulin sensitivity with aerobic exercise training in men and women at increased risk for type 2 diabetes mellitus (T2DM). Subjects were genotyped and underwent oral glucose tolerance tests before and after six months of training. Due to mis-genotyping of the BsmI polymorphism, results for that variant were not reported. There were no significant differences between FokI genotype groups in insulin sensitivity before or after training. However, among subjects who completed training, FF homozygotes had significantly higher baseline fasting glucose and insulin levels than f allele carriers. While the FokI polymorphism does not appear to mediate training-induced changes in indices of glucose and insulin metabolism, it may influence fasting glucose and insulin levels and the development of insulin resistance in individuals at increased risk for T2DM.
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