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Characterization of expressed sequen...

Meyer, Kirsten Anne.

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Characterization of expressed sequence tags from the colonial tunicate, Botryllus schlosseri.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Characterization of expressed sequence tags from the colonial tunicate, Botryllus schlosseri./
Author:	Meyer, Kirsten Anne.
Description:	100 p.
Notes:	Source: Masters Abstracts International, Volume: 37-05, page: 1406.
Contained By:	Masters Abstracts International37-05.
Subject:	Biology, Molecular. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1394120
ISBN:	9780599270381

Characterization of expressed sequence tags from the colonial tunicate, Botryllus schlosseri.
Meyer, Kirsten Anne.

Characterization of expressed sequence tags from the colonial tunicate, Botryllus schlosseri. - 100 p.

Source: Masters Abstracts International, Volume: 37-05, page: 1406.

Thesis (M.S.)--The University of New Mexico, 1999.

The focus of this project was to exploit the advantages of automated sequencing technology to search in tunicates for genes with homology to vertebrate genes with known immunological relevance. A cDNA library from Botryllus schlosseri, a colonial tunicate, was used for this purpose. Partial sequences from 214 different clones from this library were obtained and compared with known sequences in GenBank. BLAST scores of

ISBN: 9780599270381Subjects--Topical Terms:

1017719
Biology, Molecular.

Characterization of expressed sequence tags from the colonial tunicate, Botryllus schlosseri.
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020 $a 9780599270381
035 $a (UnM)AAI1394120
035 $a AAI1394120
040 $a UnM $c UnM
100 1 $a Meyer, Kirsten Anne. $3 1914086
245 1 0 $a Characterization of expressed sequence tags from the colonial tunicate, Botryllus schlosseri.
300 $a 100 p.
500 $a Source: Masters Abstracts International, Volume: 37-05, page: 1406.
502 $a Thesis (M.S.)--The University of New Mexico, 1999.
520 $a The focus of this project was to exploit the advantages of automated sequencing technology to search in tunicates for genes with homology to vertebrate genes with known immunological relevance. A cDNA library from Botryllus schlosseri, a colonial tunicate, was used for this purpose. Partial sequences from 214 different clones from this library were obtained and compared with known sequences in GenBank. BLAST scores of $< $1 0 $\ sp{-5} $ were considered indicative of significant homology. Of the 214 sequences, 93 were novel (90 with open reading frames) and 121 had significant homology with other GenBank entries (24 of these were duplicate homologs).
520 $a One of the goals of this project was to identify B. schlosseri sequences that might be relevant to internal defense and that could yield insights into the evolution of immunity in the chordates. Four B. schlosseri ESTs with significant BLAST scores to molecules known to function in internal defense were singled out for further sequence analysis: P-selectins/Von Willebrand's Factor; properdin; fibrinogen; and valosin containing protein. (Abstract shortened by UMI.)
590 $a School code: 0142.
650 4 $a Biology, Molecular. $3 1017719
650 4 $a Biology, General. $3 1018625
650 4 $a Health Sciences, Immunology. $3 1017716
690 $a 0307
690 $a 0306
690 $a 0982
710 2 0 $a The University of New Mexico. $3 1018024
773 0 $t Masters Abstracts International $g 37-05.
790 $a 0142
791 $a M.S.
792 $a 1999
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1394120