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Exercise training and sarcolemmal ca...
~
Mokelke, Eric Alain.
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Exercise training and sarcolemmal calcium(2+) handling in the heart.
Record Type:
Electronic resources : Monograph/item
Title/Author:
Exercise training and sarcolemmal calcium(2+) handling in the heart./
Author:
Mokelke, Eric Alain.
Description:
50 p.
Notes:
Source: Dissertation Abstracts International, Volume: 60-04, Section: B, page: 1379.
Contained By:
Dissertation Abstracts International60-04B.
Subject:
Biology, Animal Physiology. -
Online resource:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9925424
ISBN:
9780599250956
Exercise training and sarcolemmal calcium(2+) handling in the heart.
Mokelke, Eric Alain.
Exercise training and sarcolemmal calcium(2+) handling in the heart.
- 50 p.
Source: Dissertation Abstracts International, Volume: 60-04, Section: B, page: 1379.
Thesis (Ph.D.)--University of Colorado at Boulder, 1999.
The following studies were the first to use direct techniques on intact tissue to assess the effect of endurance exercise training on Ca2+ handling. Specifically, these studies were designed to test the long-standing, popular hypothesis that a program or endurance exercise training improves cardiac function by increasing Ca2+ influx and efflux, directly affecting cardiac excitation-contraction coupling on a beat-by-beat basis.
ISBN: 9780599250956Subjects--Topical Terms:
1017835
Biology, Animal Physiology.
Exercise training and sarcolemmal calcium(2+) handling in the heart.
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Exercise training and sarcolemmal calcium(2+) handling in the heart.
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50 p.
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Source: Dissertation Abstracts International, Volume: 60-04, Section: B, page: 1379.
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Director: Russell L. Moore.
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Thesis (Ph.D.)--University of Colorado at Boulder, 1999.
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The following studies were the first to use direct techniques on intact tissue to assess the effect of endurance exercise training on Ca2+ handling. Specifically, these studies were designed to test the long-standing, popular hypothesis that a program or endurance exercise training improves cardiac function by increasing Ca2+ influx and efflux, directly affecting cardiac excitation-contraction coupling on a beat-by-beat basis.
520
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Our results suggest that contrary to the popular hypothesis, a program of endurance exercise training does not increase the Ca2+ current density, nor the activity of the sodium calcium exchanger. These experiments did confirm for the first time electrophysiologically, that cardiac cellular hypertrophy occurs, and that perhaps there is an exercise-induced reduction in the Ca2+ buffering capacity of cardiac myocytes.
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School code: 0051.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9925424
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