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Hair analysis for the evaluation of ...

Blanchette, Phillip Stanley.

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Hair analysis for the evaluation of maternal tobacco exposure and nicotine metabolism during pregnancy.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Hair analysis for the evaluation of maternal tobacco exposure and nicotine metabolism during pregnancy./
作者:	Blanchette, Phillip Stanley.
面頁冊數:	123 p.
附註:	Source: Masters Abstracts International, Volume: 44-01, page: 0322.
Contained By:	Masters Abstracts International44-01.
標題:	Health Sciences, Obstetrics and Gynecology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MR02262
ISBN:	9780494022627

Hair analysis for the evaluation of maternal tobacco exposure and nicotine metabolism during pregnancy.
Blanchette, Phillip Stanley.

Hair analysis for the evaluation of maternal tobacco exposure and nicotine metabolism during pregnancy. - 123 p.

Source: Masters Abstracts International, Volume: 44-01, page: 0322.

Thesis (M.Sc.)--University of Toronto (Canada), 2005.

This study uses hair analysis of nicotine and cotinine to investigate maternal tobacco exposure and nicotine metabolism. Maternal hair samples and a detailed prenatal smoking survey were obtained from pregnant women in Montreal and Boston. Hair samples were sectioned to correspond with the three trimesters of pregnancy based on a hair growth rate of 1cm/month and nicotine and cotinine concentrations were measured by radioimmunoassay. Our results indicate that hair nicotine and cotinine provide a useful measure of maternal tobacco exposure, as nicotine and cotinine concentrations were reflective of exposure and cigarette consumption. Our segmental hair analysis results also indicate increased nicotine metabolism during late pregnancy. Hair cotinine concentration provides a useful estimate of potential risks associated with maternal cigarette smoking. Cotinine levels greater that or equal to 0.15 ng/mg of hair were associated with a significant reduction in gestational age and infant birth weight.

ISBN: 9780494022627Subjects--Topical Terms:

1020690
Health Sciences, Obstetrics and Gynecology.

Hair analysis for the evaluation of maternal tobacco exposure and nicotine metabolism during pregnancy.
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500 $a Source: Masters Abstracts International, Volume: 44-01, page: 0322.
502 $a Thesis (M.Sc.)--University of Toronto (Canada), 2005.
520 $a This study uses hair analysis of nicotine and cotinine to investigate maternal tobacco exposure and nicotine metabolism. Maternal hair samples and a detailed prenatal smoking survey were obtained from pregnant women in Montreal and Boston. Hair samples were sectioned to correspond with the three trimesters of pregnancy based on a hair growth rate of 1cm/month and nicotine and cotinine concentrations were measured by radioimmunoassay. Our results indicate that hair nicotine and cotinine provide a useful measure of maternal tobacco exposure, as nicotine and cotinine concentrations were reflective of exposure and cigarette consumption. Our segmental hair analysis results also indicate increased nicotine metabolism during late pregnancy. Hair cotinine concentration provides a useful estimate of potential risks associated with maternal cigarette smoking. Cotinine levels greater that or equal to 0.15 ng/mg of hair were associated with a significant reduction in gestational age and infant birth weight.
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