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Immunologic monitoring and treatment...

Sithole, Fortune.

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Immunologic monitoring and treatment of gastrointestinal parasites in dairy cattle.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Immunologic monitoring and treatment of gastrointestinal parasites in dairy cattle./
作者:	Sithole, Fortune.
面頁冊數:	210 p.
附註:	Source: Dissertation Abstracts International, Volume: 66-12, Section: B, page: 6473.
Contained By:	Dissertation Abstracts International66-12B.
標題:	Biology, Veterinary Science. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=NR10647
ISBN:	9780494106471

Immunologic monitoring and treatment of gastrointestinal parasites in dairy cattle.
Sithole, Fortune.

Immunologic monitoring and treatment of gastrointestinal parasites in dairy cattle. - 210 p.

Source: Dissertation Abstracts International, Volume: 66-12, Section: B, page: 6473.

Thesis (Ph.D.)--University of Prince Edward Island (Canada), 2005.

Gastrointestinal (GIT) nematodes have been shown to have a detrimental effect on milk production and reproduction in adult dairy cows. Fecal egg counts (FEC) have been shown to be unreliable measures of worm burden in adult cows. An indirect crude adult worn Ostertagia ostertagi enzyme-linked immunosorbent assay (ELISA) has shown promise in its ability to measure worm burden. ELISA optical density ratio (ODR) values are associated with milk production and pasture exposure in a predictable way. Eprinomecin treatment of adult dairy cows at is associated with increased in milk production in pastured herds. The ELISA has a lot of promise in its ability to predict a milk production or reproduction response to anthelmintic treatment. The ELISA could be used as a herd health management tool to predict cows/herds that will benefit from deworming. The main goals of this study were (1) to establish the benefit of deworming cows with eprinomectin at calving on milk production and reproduction in 64 dairy herds with limited outdoor exposure in the summer, (2) to evaluate the ability of a bulk milk ELISA in identifying dairy herds whose milk production and reproduction would benefit from eprinomectin treatment, (3) to evaluate the accuracy of DHI reproduction records, (4) to evaluate the association between GIT nematodes and energy status of cows at calving, and (5) to further develop the ELISA by evaluating a selection of blocking agents, conjugates and antigens.

ISBN: 9780494106471Subjects--Topical Terms:

1021733
Biology, Veterinary Science.

Immunologic monitoring and treatment of gastrointestinal parasites in dairy cattle.
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245 1 0 $a Immunologic monitoring and treatment of gastrointestinal parasites in dairy cattle.
300 $a 210 p.
500 $a Source: Dissertation Abstracts International, Volume: 66-12, Section: B, page: 6473.
502 $a Thesis (Ph.D.)--University of Prince Edward Island (Canada), 2005.
520 $a Gastrointestinal (GIT) nematodes have been shown to have a detrimental effect on milk production and reproduction in adult dairy cows. Fecal egg counts (FEC) have been shown to be unreliable measures of worm burden in adult cows. An indirect crude adult worn Ostertagia ostertagi enzyme-linked immunosorbent assay (ELISA) has shown promise in its ability to measure worm burden. ELISA optical density ratio (ODR) values are associated with milk production and pasture exposure in a predictable way. Eprinomecin treatment of adult dairy cows at is associated with increased in milk production in pastured herds. The ELISA has a lot of promise in its ability to predict a milk production or reproduction response to anthelmintic treatment. The ELISA could be used as a herd health management tool to predict cows/herds that will benefit from deworming. The main goals of this study were (1) to establish the benefit of deworming cows with eprinomectin at calving on milk production and reproduction in 64 dairy herds with limited outdoor exposure in the summer, (2) to evaluate the ability of a bulk milk ELISA in identifying dairy herds whose milk production and reproduction would benefit from eprinomectin treatment, (3) to evaluate the accuracy of DHI reproduction records, (4) to evaluate the association between GIT nematodes and energy status of cows at calving, and (5) to further develop the ELISA by evaluating a selection of blocking agents, conjugates and antigens.
520 $a Eprinomectin treatment did not improve milk production and reproduction in herds with limited pasture exposure. However, it did provide some evidence that the ELISA may be more effective than FEC at identifying herds in which a positive treatment effect might be expected.
520 $a Because earlier studies found a significant treatment effect in cows that were dewormed around calving, a study to establish the impact of deworming on the peripartum energy status, was conducted. Parasite burden in the previous lactation, had a negative impact on the energy status of the cows, at ODR values greater than 0.4. However, the lack of an anthelmintic treatment effect may have been due to the low parasite burdens in the study herds.
520 $a The stability of ELISA plates prepared with one of 3 blocking agents and used with one of 2 conjugates (monoclonal and polyclonal) at various time intervals after preparation of the plates, was assessed. ODR values of all the blocking agent/conjugate combinations were consistent over a year. Two of the blocking agents enabled plates to be stored dry, at room temperature, making them convenient to use and transport. ELISA results suggested that the larval stage 4 and adult excretory/secretory antigens elicit a stronger humoral immune response than the crude adult antigen. Further studies to compare the abilities of the antigens in identifying cows/herds that would benefit from anthelmintic treatment need to be conducted. (Abstract shortened by UMI.)
590 $a School code: 1108.
650 4 $a Biology, Veterinary Science. $3 1021733
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