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Search procedure for identifying gen...
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Milanov, Valentin B.
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Search procedure for identifying gene-gene interaction based on entropy measures.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Search procedure for identifying gene-gene interaction based on entropy measures./
作者:
Milanov, Valentin B.
面頁冊數:
106 p.
附註:
Source: Dissertation Abstracts International, Volume: 66-03, Section: B, page: 1538.
Contained By:
Dissertation Abstracts International66-03B.
標題:
Statistics. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3167434
ISBN:
0542032422
Search procedure for identifying gene-gene interaction based on entropy measures.
Milanov, Valentin B.
Search procedure for identifying gene-gene interaction based on entropy measures.
- 106 p.
Source: Dissertation Abstracts International, Volume: 66-03, Section: B, page: 1538.
Thesis (Ph.D.)--Michigan Technological University, 2005.
In this work we propose and study four novel search procedures for identifying susceptibility genes for complex human diseases among thousands of candidate genes genome-wide and, in particular gene-gene interaction. The proposed methods are based on a float search algorithm utilizing criterion functions based on entropy based measures of association. The search procedures utilize genotype data from a large set of independent markers under case-control design. We show, through extensive simulations and comparisons, that the proposed search procedure may have higher discovery rates than other methods for identification of gene-gene interaction currently used.
ISBN: 0542032422Subjects--Topical Terms:
517247
Statistics.
Search procedure for identifying gene-gene interaction based on entropy measures.
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Source: Dissertation Abstracts International, Volume: 66-03, Section: B, page: 1538.
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In this work we propose and study four novel search procedures for identifying susceptibility genes for complex human diseases among thousands of candidate genes genome-wide and, in particular gene-gene interaction. The proposed methods are based on a float search algorithm utilizing criterion functions based on entropy based measures of association. The search procedures utilize genotype data from a large set of independent markers under case-control design. We show, through extensive simulations and comparisons, that the proposed search procedure may have higher discovery rates than other methods for identification of gene-gene interaction currently used.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3167434
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