東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Ultrasonic thermal strain imaging.

Shi, Yan.

Linked to FindBook

Google Book

Amazon

博客來

Ultrasonic thermal strain imaging.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Ultrasonic thermal strain imaging./
Author:	Shi, Yan.
Description:	124 p.
Notes:	Source: Dissertation Abstracts International, Volume: 66-02, Section: B, page: 1020.
Contained By:	Dissertation Abstracts International66-02B.
Subject:	Engineering, Biomedical. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3163929
ISBN:	0496985949

Ultrasonic thermal strain imaging.
Shi, Yan.

Ultrasonic thermal strain imaging. - 124 p.

Source: Dissertation Abstracts International, Volume: 66-02, Section: B, page: 1020.

Thesis (Ph.D.)--University of Michigan, 2005.

Cardiovascular disease is the leading cause of death in the industrialized world. It results in about 1 million deaths in the US each year, with acute coronary heart disease accounting for the majority. The underlying mechanism of most acute coronary events is the disruption of atherosclerotic coronary plaques. These rupture-prone plaques, or "vulnerable plaques", are mainly characterized by a lipid-rich core and a thin fibrous cap.

ISBN: 0496985949Subjects--Topical Terms:

1017684
Engineering, Biomedical.

Ultrasonic thermal strain imaging.
LDR:03235nmm 2200301 4500 001 1816988
005 20060816133855.5
008 130610s2005 eng d
020 $a 0496985949
035 $a (UnM)AAI3163929
035 $a AAI3163929
040 $a UnM $c UnM
100 1 $a Shi, Yan. $3 1906354
245 1 0 $a Ultrasonic thermal strain imaging.
300 $a 124 p.
500 $a Source: Dissertation Abstracts International, Volume: 66-02, Section: B, page: 1020.
500 $a Chair: Matthew O'Donnell.
502 $a Thesis (Ph.D.)--University of Michigan, 2005.
520 $a Cardiovascular disease is the leading cause of death in the industrialized world. It results in about 1 million deaths in the US each year, with acute coronary heart disease accounting for the majority. The underlying mechanism of most acute coronary events is the disruption of atherosclerotic coronary plaques. These rupture-prone plaques, or "vulnerable plaques", are mainly characterized by a lipid-rich core and a thin fibrous cap.
520 $a An ultrasonic tissue differentiation technique, thermal strain imaging (TSI), has been proposed for vulnerable plaque detection. It employs cross-correlation algorithms to create thermal strain images based on the temperature dependence of sound speed. Due to the strong contrast between water-bearing and lipid-bearing tissue, it has the potential to distinguish a lipid-laden lesion from the arterial vascular wall. Excised rat and pig tissues were tested using 10MHz and 85MHz single element transducers and a surface microwave antenna as the heating source. Results demonstrated strong thermal strain contrast between water-based liver and fat, suggesting the feasibility of TSI in tissue separation. A phantom experiment using an intravascular ultrasound (IVUS) imaging array was performed to further validate the concept, where the phantom consisted of rubber and gelatin layers to mimic plaque and the arterial wall, respectively. Results agree reasonably well with theoretical predictions, and estimated layer boundaries match phantom physical dimensions. Simulations performed on an atherosclerotic artery model including a lipid-filled plaque also verified experimental results.
520 $a The major challenge for in vivo application of TSI is cardiac motion, including bulk motion and tissue deformation. Simulations based on the same artery model demonstrate effective bulk motion compensation can be achieved within a certain motion range using spatial interpolation. We also propose a practical imaging scheme to minimize mechanical strains caused by cardiac motion based on a linear least squares fitting strategy. This scheme was tested on clinical IVUS data by artificially superimposing thermal strains, corresponding to different temperature rises, on strain images generated from the clinical data. Results suggest a 1--2°C temperature rise is required to detect lipids in an atherosclerotic plaque in vivo.
590 $a School code: 0127.
650 4 $a Engineering, Biomedical. $3 1017684
650 4 $a Health Sciences, Radiology. $3 1019076
690 $a 0541
690 $a 0574
710 2 0 $a University of Michigan. $3 777416
773 0 $t Dissertation Abstracts International $g 66-02B.
790 1 0 $a O'Donnell, Matthew, $e advisor
790 $a 0127
791 $a Ph.D.
792 $a 2005
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3163929