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Neural correlates of associative and...

Achim, Amelie M.

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Neural correlates of associative and item memory.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Neural correlates of associative and item memory./
作者:	Achim, Amelie M.
面頁冊數:	116 p.
附註:	Source: Masters Abstracts International, Volume: 43-04, page: 1216.
Contained By:	Masters Abstracts International43-04.
標題:	Biology, Neuroscience. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MQ98583
ISBN:	0612985830

Neural correlates of associative and item memory.
Achim, Amelie M.

Neural correlates of associative and item memory. - 116 p.

Source: Masters Abstracts International, Volume: 43-04, page: 1216.

Thesis (M.Sc.)--McGill University (Canada), 2004.

Dissociation between memory for individual items and memory for associations has been reported in behavioral neurosciences, clinical populations and cognitive studies. At the brain level, this dissociation could reflect distinct patterns of activation for encoding and/or retrieval of items and associations. We used event-related functional Magnetic Resonance Imaging to assess neural correlates of item and associative encoding and retrieval in eighteen healthy subjects. During encoding, subjects memorized doubles (two identical images) and pairs (two different images). During retrieval, subjects made item recognition judgments (old versus new items) and associative recognition judgments (intact versus rearranged pairs). Greater hippocampal activation was observed for associative relative to item encoding, but also for item relative to associative recognition. This pattern of hippocampal activation is consistent with previous neuroimaging studies of associative encoding, but also suggests that at retrieval other processes such as novelty detection could recruit the hippocampus to a greater extent than associative recognition. In the prefrontal cortex, we observed right and left activation for associative and item encoding, respectively. At retrieval, the opposite pattern was observed with left prefrontal activation for associative and bilateral activation for item recognition. This pattern of prefrontal activation shows the implication of the prefrontal cortex in memory for both types of material, although with a different lateralization. Overall, these results show the importance of examining the memory stages when comparing neural correlates of item and associative memory.

ISBN: 0612985830Subjects--Topical Terms:

1017680
Biology, Neuroscience.

Neural correlates of associative and item memory.
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520 $a Dissociation between memory for individual items and memory for associations has been reported in behavioral neurosciences, clinical populations and cognitive studies. At the brain level, this dissociation could reflect distinct patterns of activation for encoding and/or retrieval of items and associations. We used event-related functional Magnetic Resonance Imaging to assess neural correlates of item and associative encoding and retrieval in eighteen healthy subjects. During encoding, subjects memorized doubles (two identical images) and pairs (two different images). During retrieval, subjects made item recognition judgments (old versus new items) and associative recognition judgments (intact versus rearranged pairs). Greater hippocampal activation was observed for associative relative to item encoding, but also for item relative to associative recognition. This pattern of hippocampal activation is consistent with previous neuroimaging studies of associative encoding, but also suggests that at retrieval other processes such as novelty detection could recruit the hippocampus to a greater extent than associative recognition. In the prefrontal cortex, we observed right and left activation for associative and item encoding, respectively. At retrieval, the opposite pattern was observed with left prefrontal activation for associative and bilateral activation for item recognition. This pattern of prefrontal activation shows the implication of the prefrontal cortex in memory for both types of material, although with a different lateralization. Overall, these results show the importance of examining the memory stages when comparing neural correlates of item and associative memory.
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