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Effect of pharmaceutical innovation ...

Shah, Manan Bhupendra.

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Effect of pharmaceutical innovation on health care utilization and expenditure.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Effect of pharmaceutical innovation on health care utilization and expenditure./
作者:	Shah, Manan Bhupendra.
面頁冊數:	129 p.
附註:	Source: Dissertation Abstracts International, Volume: 66-07, Section: B, page: 3657.
Contained By:	Dissertation Abstracts International66-07B.
標題:	Health Sciences, Pharmacy. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3181985
ISBN:	054222335X

Effect of pharmaceutical innovation on health care utilization and expenditure.
Shah, Manan Bhupendra.

Effect of pharmaceutical innovation on health care utilization and expenditure. - 129 p.

Source: Dissertation Abstracts International, Volume: 66-07, Section: B, page: 3657.

Thesis (Ph.D.)--University of South Carolina, 2005.

The purpose of the study was to evaluate the impact of innovative drug therapy for schizophrenia management on health care utilization and expenditure from a third-party payer perspective.

ISBN: 054222335XSubjects--Topical Terms:

1017737
Health Sciences, Pharmacy.

Effect of pharmaceutical innovation on health care utilization and expenditure.
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245 1 0 $a Effect of pharmaceutical innovation on health care utilization and expenditure.
300 $a 129 p.
500 $a Source: Dissertation Abstracts International, Volume: 66-07, Section: B, page: 3657.
500 $a Director: Michael Dickson.
502 $a Thesis (Ph.D.)--University of South Carolina, 2005.
520 $a The purpose of the study was to evaluate the impact of innovative drug therapy for schizophrenia management on health care utilization and expenditure from a third-party payer perspective.
520 $a Data beginning July 1, 1994 through December 31, 2002 was obtained from South Carolina Medicaid to conduct the study. Patients were required to have at least one ambulatory or hospital diagnosis for schizophrenia and a prescription for an antipsychotic (AP) within 30 days after diagnosis or within 90 days prior to diagnosis. Patients were excluded if they had a diagnosis for schizoaffective disorder or bipolar disorder, were less than 18 years of age, or were greater than 64 years of age. Patients were placed into mutually exclusive groups based on AP utilization patterns. Count models were used to assess two-year utilization rates, and log-transformed ordinary least squares regression models were used to evaluate two-year expenditure.
520 $a There were 5,815 patients who met all selection criteria. Of these, 3,366 patients were monotherapy users, and 2,449 patients were combination therapy users. Evaluation of the monotherapy users revealed that the atypical cohort offered no significant benefit in terms of health care utilization when compared to conventional or depot cohorts. Furthermore, the atypical cohort did not provide a medical cost offset, thus incurring higher total health care expenditure compared to conventional and depot cohorts. Results also revealed that atypical APs were not associated with improved compliance compared with the other APs. Post-hoc analysis comparing patients from the combination therapy group to patients in the atypical monotherapy cohort revealed that the atypical and depot combination therapy cohorts yielded higher hospital and ambulatory expenditure and were statistically similar in terms of total health care expenditure. However, the conventional combination therapy cohort yielded lower total health care expenditure compared to the atypical monotherapy cohort.
520 $a Innovative drug therapy for the treatment of schizophrenia (i.e., atypical APs) was not associated with lower utilization of other health care services and, therefore, was not associated with lower health care expenditure. Moreover, atypical APs exhibited the lowest rates of medication compliance. However, some trends were recognized that warrant further research.
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