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Anticancer activity of two dietary p...
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Merchant, Kendra T.
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Anticancer activity of two dietary phytochemicals: Genistein and beta-lapachone.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Anticancer activity of two dietary phytochemicals: Genistein and beta-lapachone./
作者:
Merchant, Kendra T.
面頁冊數:
52 p.
附註:
Source: Masters Abstracts International, Volume: 43-06, page: 2074.
Contained By:
Masters Abstracts International43-06.
標題:
Biology, Cell. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1426985
ISBN:
054213439X
Anticancer activity of two dietary phytochemicals: Genistein and beta-lapachone.
Merchant, Kendra T.
Anticancer activity of two dietary phytochemicals: Genistein and beta-lapachone.
- 52 p.
Source: Masters Abstracts International, Volume: 43-06, page: 2074.
Thesis (M.S.)--Florida Atlantic University, 2005.
Phytochemicals are biologically active secondary plant metabolites that have been shown to exhibit anti-cancer activity. The dietary phytochemicals genistein isoflavone and beta-lapachone, were investigated to determine their effect on the growth of human prostate adenocarcinoma cells in vitro. The cells were exposed to varying concentrations of both phytochemicals in single and combination treatments for specified time periods and their effect was determined using post-treatment cell viability, treatment-induced apoptosis and cell signaling assays. The overall results revealed that both phytochemicals inhibited cell growth and proliferation and induced apoptosis in a dose-dependent manner for both single and combination treatments. However, combination treatments were not significantly more effective than single treatment with either drug. Both phytochemicals could therefore offer therapeutic efficacy in human prostate adenocarcinoma.
ISBN: 054213439XSubjects--Topical Terms:
1017686
Biology, Cell.
Anticancer activity of two dietary phytochemicals: Genistein and beta-lapachone.
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Phytochemicals are biologically active secondary plant metabolites that have been shown to exhibit anti-cancer activity. The dietary phytochemicals genistein isoflavone and beta-lapachone, were investigated to determine their effect on the growth of human prostate adenocarcinoma cells in vitro. The cells were exposed to varying concentrations of both phytochemicals in single and combination treatments for specified time periods and their effect was determined using post-treatment cell viability, treatment-induced apoptosis and cell signaling assays. The overall results revealed that both phytochemicals inhibited cell growth and proliferation and induced apoptosis in a dose-dependent manner for both single and combination treatments. However, combination treatments were not significantly more effective than single treatment with either drug. Both phytochemicals could therefore offer therapeutic efficacy in human prostate adenocarcinoma.
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