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Graphical Representation of Biologic...

Yu, Chenglong.

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Graphical Representation of Biological Sequences and Its Applications.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Graphical Representation of Biological Sequences and Its Applications./
作者:	Yu, Chenglong.
面頁冊數:	64 p.
附註:	Source: Dissertation Abstracts International, Volume: 72-04, Section: B, page: 2189.
Contained By:	Dissertation Abstracts International72-04B.
標題:	Biology, Molecular. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3445967
ISBN:	9781124494388

Graphical Representation of Biological Sequences and Its Applications.
Yu, Chenglong.

Graphical Representation of Biological Sequences and Its Applications. - 64 p.

Source: Dissertation Abstracts International, Volume: 72-04, Section: B, page: 2189.

Thesis (Ph.D.)--The Chinese University of Hong Kong (Hong Kong), 2010.

Among all existing alignment-free methods for comparing biological sequences, the sequence graphical representation provides a simple approach to view, sort, and compare gene structures. The aim of graphical representation is to display DNA or protein sequences graphically so that we can easily find out visually how similar or how different they are. Of course, only the visual comparison of sequences is not enough for the follow-up research work. We need more accurate comparison. This leads us to develop the application of the graphical representation for biological sequences.

ISBN: 9781124494388Subjects--Topical Terms:

1017719
Biology, Molecular.

Graphical Representation of Biological Sequences and Its Applications.
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500 $a Source: Dissertation Abstracts International, Volume: 72-04, Section: B, page: 2189.
500 $a Adviser: Luk Hing Sun.
502 $a Thesis (Ph.D.)--The Chinese University of Hong Kong (Hong Kong), 2010.
520 $a Among all existing alignment-free methods for comparing biological sequences, the sequence graphical representation provides a simple approach to view, sort, and compare gene structures. The aim of graphical representation is to display DNA or protein sequences graphically so that we can easily find out visually how similar or how different they are. Of course, only the visual comparison of sequences is not enough for the follow-up research work. We need more accurate comparison. This leads us to develop the application of the graphical representation for biological sequences.
520 $a In this thesis, we have two main contributions: (1) We construct a protein map with the help of our proposed new graphical representation for protein sequences. Each protein sequence can be represented as a point in this map, and cluster analysis of proteins can be performed for comparison between the points. This protein map can be used to mathematically specify the similarity of two proteins and predict properties of an unknown protein based on its amino acid sequence. (2) We construct a novel genome space with biological geometry, which is a subspace in RN . In this space each point corresponds to a genome. The natural distance between two points in the genome space reflects the biological distance between these two genomes. Our genome space will provide a new powerful tool for analyzing the classification of genomes and their phylogenetic relationships.
590 $a School code: 1307.
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650 4 $a Applied Mathematics. $3 1669109
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710 2 $a The Chinese University of Hong Kong (Hong Kong). $3 1017547
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