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Instrumentation for interstitial pho...

Liu, Weiyang.

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Instrumentation for interstitial photodynamic therapy of prostatic carcinoma.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Instrumentation for interstitial photodynamic therapy of prostatic carcinoma./
作者:	Liu, Weiyang.
面頁冊數:	184 p.
附註:	Source: Masters Abstracts International, Volume: 48-04, page: 2407.
Contained By:	Masters Abstracts International48-04.
標題:	Engineering, Biomedical. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MR56662
ISBN:	9780494566626

Instrumentation for interstitial photodynamic therapy of prostatic carcinoma.
Liu, Weiyang.

Instrumentation for interstitial photodynamic therapy of prostatic carcinoma. - 184 p.

Source: Masters Abstracts International, Volume: 48-04, page: 2407.

Thesis (M.Sc.)--University of Alberta (Canada), 2010.

This thesis encompasses the development and testing of an interstitial photodynamic therapy (iPDT) system for the treatment of prostate cancer. It begins with the optical characterization of a novel photosensitizer (SL-052) followed by a study of tissue optics as it applies to iPDT. The design and integration of a time-fractionated light delivery system with real-time spectral detection is then examined. An optical phantom test medium is formulated and in vitro system operation and testing is performed. Finally, in vivo experiments are performed on animal models with a focus on canine prostate iPDT. Unique optical results with dosimetric relevance are discovered and investigated. This includes metrics for optically measuring local in vivo SL-052 concentrations in real-time as well as novel oscillatory drug photobleaching and recovery behavior during time-fractionated light delivery.

ISBN: 9780494566626Subjects--Topical Terms:

1017684
Engineering, Biomedical.

Instrumentation for interstitial photodynamic therapy of prostatic carcinoma.
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