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Birth cohort analysis of hypertensio...

Li, Fangyong.

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Birth cohort analysis of hypertension in China.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Birth cohort analysis of hypertension in China./
作者:	Li, Fangyong.
面頁冊數:	119 p.
附註:	Source: Masters Abstracts International, Volume: 49-01, page: 0365.
Contained By:	Masters Abstracts International49-01.
標題:	Biology, Biostatistics. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1480318
ISBN:	9781124180359

Birth cohort analysis of hypertension in China.
Li, Fangyong.

Birth cohort analysis of hypertension in China. - 119 p.

Source: Masters Abstracts International, Volume: 49-01, page: 0365.

Thesis (M.P.H.)--Yale University, 2010.

This study conducted a secondary analysis to examine the hypertension risk among different generations of Chinese using China Health and Nutrition Survey data. This is an accelerated longitudinal panel study in that same individuals were followed up from 1997 to 2006, including 7,710 participants who were classified into 5 birth cohorts according to birth date by decade from 30's to 70's. They came from 8 provinces in a line from south to north China. Primary outcome of the study was systolic and diastolic blood pressure. The secondary outcome was binary one defined as hypertension yes or not using conventional criteria.

ISBN: 9781124180359Subjects--Topical Terms:

1018416
Biology, Biostatistics.

Birth cohort analysis of hypertension in China.
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245 1 0 $a Birth cohort analysis of hypertension in China.
300 $a 119 p.
500 $a Source: Masters Abstracts International, Volume: 49-01, page: 0365.
500 $a Advisers: Daniel Zelterman; Haiqun Lin.
502 $a Thesis (M.P.H.)--Yale University, 2010.
520 $a This study conducted a secondary analysis to examine the hypertension risk among different generations of Chinese using China Health and Nutrition Survey data. This is an accelerated longitudinal panel study in that same individuals were followed up from 1997 to 2006, including 7,710 participants who were classified into 5 birth cohorts according to birth date by decade from 30's to 70's. They came from 8 provinces in a line from south to north China. Primary outcome of the study was systolic and diastolic blood pressure. The secondary outcome was binary one defined as hypertension yes or not using conventional criteria.
520 $a Three linear mixed model-based approaches were used to disentangle the age, period and cohort effects. Growth curve random intercept model provided most precise adjustment of curvature age effect thus was preferable. The age trajectories of systolic blood pressure for cohort 70's and diastolic blood pressure for cohort 70's and 60's stood out from other cohorts, predicating higher risk of hypertension among younger generation. Specifically, LSmean of systolic blood pressure for 70's was 121.9 +/- 0.6 mmHg, which was significantly higher than that of 50's and 60's. Lsmeans of diastolic blood pressure for 70's was 80 +/- 0.4 mmHg, which was significantly higher than all other generations.
520 $a GEE model on binary outcome didn't find significant cohort effect. However, consistent with finding from continuous outcome, female was less likely to be hypertensive than male, and those from rural region were less likely to be hypertensive than those from urban. Interestingly, there was a spacial trend of the risk of hypertension. The odds of being hypertension increased gradually from south to north China.
520 $a The finding of this study would be useful to plan hypertension prevention in China.
590 $a School code: 0265.
650 4 $a Biology, Biostatistics. $3 1018416
650 4 $a Health Sciences, Epidemiology. $3 1019544
690 $a 0308
690 $a 0766
710 2 $a Yale University. $b School of Public Health. $3 1679063
773 0 $t Masters Abstracts International $g 49-01.
790 1 0 $a Zelterman, Daniel, $e advisor
790 1 0 $a Lin, Haiqun, $e advisor
790 $a 0265
791 $a M.P.H.
792 $a 2010
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