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Effects of long-chain fatty acids on...
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Caldari-Torres, Cristina.
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Effects of long-chain fatty acids on production, metabolism and immunity of Holstein cows.
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Effects of long-chain fatty acids on production, metabolism and immunity of Holstein cows./
作者:
Caldari-Torres, Cristina.
面頁冊數:
205 p.
附註:
Source: Dissertation Abstracts International, Volume: 71-11, Section: B, page: 6497.
Contained By:
Dissertation Abstracts International71-11B.
標題:
Agriculture, Animal Culture and Nutrition. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3425512
ISBN:
9781124285597
Effects of long-chain fatty acids on production, metabolism and immunity of Holstein cows.
Caldari-Torres, Cristina.
Effects of long-chain fatty acids on production, metabolism and immunity of Holstein cows.
- 205 p.
Source: Dissertation Abstracts International, Volume: 71-11, Section: B, page: 6497.
Thesis (Ph.D.)--University of Florida, 2009.
A series of in vitro experiments were conducted to examine the effects of long-chain fatty acids (LCFAs) on mitogen-stimulated cytokine production by bovine peripheral blood mononuclear cells (PBMCs). Additionally, an in vivo experiment testing the effect of dietary n-6 and trans fatty acids (tFAs) on production, metabolism and uterine health of periparturient Holstein cows was conducted.
ISBN: 9781124285597Subjects--Topical Terms:
1017857
Agriculture, Animal Culture and Nutrition.
Effects of long-chain fatty acids on production, metabolism and immunity of Holstein cows.
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Source: Dissertation Abstracts International, Volume: 71-11, Section: B, page: 6497.
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A series of in vitro experiments were conducted to examine the effects of long-chain fatty acids (LCFAs) on mitogen-stimulated cytokine production by bovine peripheral blood mononuclear cells (PBMCs). Additionally, an in vivo experiment testing the effect of dietary n-6 and trans fatty acids (tFAs) on production, metabolism and uterine health of periparturient Holstein cows was conducted.
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Bovine PBMCs co-treated with trans-monounsaturated fatty acids (FAs) produced more concanavalin A (ConA)-stimulated pro-inflammatory cytokines than did cells treated with cis-monounsaturated FAs. These data further support that dietary tFAs induce systemic inflammation in mammalian species. Addition of the cis-9, trans-11(c9,t11) and trans -10, cis-12 (t10,c12) conjugated linoleic acid (CLA) isomers to the culture media did not affect ConA-stimulated cytokine production by bovine PBMCs. Eicosapentaenoic acid (EPA) and linolenic acid (LNA) attenuated ConA-stimulated cytokine production by bovine PBMCs, with LNA suppressing cytokine production to a lesser extent than EPA.
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Multiparous dairy cows were fed one of three dietary treatments from approximately 29 d prior to estimated calving date through 49 d postpartum. The control diet contained a 90% saturated fat supplement, at 1.5% of dietary dry matter (DM). The second and third dietary treatments contained calcium salts of tFAs (61% trans C18:1 isomers, tFA) and calcium salts of safflower oil (55% linoleic acid, LA), respectively, at 1.8% of dietary DM. Feeding supplemental LA to multiparous Holstein cows resulted in an earlier return to positive energy balance than those fed the saturated FA or tFA supplements. This improvement in energy status was primarily due to a decreased concentration in milk fat. Plasma concentrations of non-esterified fatty acids were lower and that of glucose were greater in cows allocated to the LA dietary treatment, indicating an improved metabolic status. These animals also demonstrated better uterine health on d 7 postpartum and had greater accumulated progesterone concentration in plasma by day 50 postpartum than animals in the other two treatment groups. Studies with a larger number of animals are warranted to fully document the effect of periparturient fat supplementation on uterine health and reproductive efficiency in dairy cows.
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