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Effects of growing programs and beta...

Stein, Daniel Ray.

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Effects of growing programs and beta-adrenergic agonists on gene expression in adipose tissue depots in finishing beef steers.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Effects of growing programs and beta-adrenergic agonists on gene expression in adipose tissue depots in finishing beef steers./
Author:	Stein, Daniel Ray.
Description:	301 p.
Notes:	Source: Dissertation Abstracts International, Volume: 70-09, Section: B, page: 5241.
Contained By:	Dissertation Abstracts International70-09B.
Subject:	Agriculture, Animal Culture and Nutrition. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3372216
ISBN:	9781109348781

Effects of growing programs and beta-adrenergic agonists on gene expression in adipose tissue depots in finishing beef steers.
Stein, Daniel Ray.

Effects of growing programs and beta-adrenergic agonists on gene expression in adipose tissue depots in finishing beef steers. - 301 p.

Source: Dissertation Abstracts International, Volume: 70-09, Section: B, page: 5241.

Thesis (Ph.D.)--Oklahoma State University, 2009.

Scope and Method of Study. As adipose tissue accretion in the bovine is controlled by a balance of adipocyte proliferation and differentiation; it is essential to evaluate how diet or the administration of exogenous compounds, such as beta-agonists, affects and/or regulates adipocyte proliferation in order to improve the quality of the beef produced. Knowledge and understanding of the relationships between mechanisms regulating metabolic and signaling pathways and other contributing factors which orchestrate adipose tissue deposition within and between adipose tissue depots could possibly be integrated into management practices in a value-based marketing system to produce a consistent and desirable product that would ultimately enhance consumer beef consumption, increase efficiency of production, and increase profitability for the beef industry.

ISBN: 9781109348781Subjects--Topical Terms:

1017857
Agriculture, Animal Culture and Nutrition.

Effects of growing programs and beta-adrenergic agonists on gene expression in adipose tissue depots in finishing beef steers.
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020 $a 9781109348781
035 $a (UMI)AAI3372216
035 $a AAI3372216
040 $a UMI $c UMI
100 1 $a Stein, Daniel Ray. $3 1676750
245 1 0 $a Effects of growing programs and beta-adrenergic agonists on gene expression in adipose tissue depots in finishing beef steers.
300 $a 301 p.
500 $a Source: Dissertation Abstracts International, Volume: 70-09, Section: B, page: 5241.
500 $a Adviser: Clint R. Krehbiel.
502 $a Thesis (Ph.D.)--Oklahoma State University, 2009.
520 $a Scope and Method of Study. As adipose tissue accretion in the bovine is controlled by a balance of adipocyte proliferation and differentiation; it is essential to evaluate how diet or the administration of exogenous compounds, such as beta-agonists, affects and/or regulates adipocyte proliferation in order to improve the quality of the beef produced. Knowledge and understanding of the relationships between mechanisms regulating metabolic and signaling pathways and other contributing factors which orchestrate adipose tissue deposition within and between adipose tissue depots could possibly be integrated into management practices in a value-based marketing system to produce a consistent and desirable product that would ultimately enhance consumer beef consumption, increase efficiency of production, and increase profitability for the beef industry.
520 $a Findings and Conclusions. Three hundred sixty-eight array elements were observed to be differentially expressed between s.c. and i.m. adipose tissue depots in the Initial and/or one of the diets of the Growing Phase. Two hundred forty-eight array elements were found to be differentially expressed between s.c. and i.m. adipose tissue depots in at least one of the four treatment diets during the Finishing Phase. The data indicates the metabolic machinery for adipose tissue accretion was down-regulated in the i.m. adipose tissue depot compared to s.c. adipose tissue depot and the main effect of previous diet could possibly influence adipose tissue deposition at the end of both the growing and finishing production phases in beef cattle. Microarray analysis showed no array elements to be differentially expressed in the i.m., s.c., or visceral adipose tissue depots or Longissimus muscle tissue between the control steers and steers supplemented with Zilpaterol hydrochloride for 20 d with a 3-d withdrawal. Of the genes selected for validation using RT-PCR in respective tissues, only cytochrome C-1 and beta2-AR in i.m. adipose tissue and beta1-AR in s.c. adipose tissue did not support the results of the microarray analysis. RT-PCR revealed cytochrome C-1, beta1-AR, and beta2-AR mRNA expression to be up-regulated threefold, fourfold and fourfold in Zilpaterol hydrochloride supplemented steers vs. control steers, respectively.
590 $a School code: 0664.
650 4 $a Agriculture, Animal Culture and Nutrition. $3 1017857
690 $a 0475
710 2 $a Oklahoma State University. $b Animal Science. $3 1272629
773 0 $t Dissertation Abstracts International $g 70-09B.
790 1 0 $a Krehbiel, Clint R., $e advisor
790 1 0 $a DeSilva, Udaya E. $e committee member
790 1 0 $a Ayoubi, Patricia J. $e committee member
790 1 0 $a Morgan, J. Brad $e committee member
790 1 0 $a Geisert, Rodney D. $e committee member
790 $a 0664
791 $a Ph.D.
792 $a 2009
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3372216