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Empirical essays on alliances and in...

Diestre, Luis.

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Empirical essays on alliances and innovation in the biopharmaceutical industry.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Empirical essays on alliances and innovation in the biopharmaceutical industry./
Author:	Diestre, Luis.
Description:	155 p.
Notes:	Source: Dissertation Abstracts International, Volume: 70-07, Section: A, page: 2603.
Contained By:	Dissertation Abstracts International70-07A.
Subject:	Business Administration, Entrepreneurship. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3368511
ISBN:	9781109292305

Empirical essays on alliances and innovation in the biopharmaceutical industry.
Diestre, Luis.

Empirical essays on alliances and innovation in the biopharmaceutical industry. - 155 p.

Source: Dissertation Abstracts International, Volume: 70-07, Section: A, page: 2603.

Thesis (Ph.D.)--University of Southern California, 2009.

In this dissertation I discuss two empirical studies that examine how different types of firms in the biopharmaceutical industry approach different types of challenges posed by radical and uncertain technological change. In the first empirical essay I explore the role of different sources of experience in understanding incumbent pharmaceutical firms' decisions to develop new drugs. In the second empirical essay I explore how emerging new biotechnology ventures make alliance partner selection decisions as a function of both partner attractiveness and the risks of appropriation that arise from establishing alliances with incumbent pharmaceuticals.

ISBN: 9781109292305Subjects--Topical Terms:

1026793
Business Administration, Entrepreneurship.

Empirical essays on alliances and innovation in the biopharmaceutical industry.
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100 1 $a Diestre, Luis. $3 1675389
245 1 0 $a Empirical essays on alliances and innovation in the biopharmaceutical industry.
300 $a 155 p.
500 $a Source: Dissertation Abstracts International, Volume: 70-07, Section: A, page: 2603.
500 $a Adviser: Nandini Rajagopalan.
502 $a Thesis (Ph.D.)--University of Southern California, 2009.
520 $a In this dissertation I discuss two empirical studies that examine how different types of firms in the biopharmaceutical industry approach different types of challenges posed by radical and uncertain technological change. In the first empirical essay I explore the role of different sources of experience in understanding incumbent pharmaceutical firms' decisions to develop new drugs. In the second empirical essay I explore how emerging new biotechnology ventures make alliance partner selection decisions as a function of both partner attractiveness and the risks of appropriation that arise from establishing alliances with incumbent pharmaceuticals.
520 $a In the first essay I examine the effects of different types of experience on the number of new products that a pharmaceutical firm develops for specific therapeutic areas. I focus on two sources of experience: a firm's internal experience and the experience of the members of the board of directors. First, I find that a firm's internal experience, which arises from prior new-product developments, has a curvilinear effect on the extent of new-product developments for a specific therapeutic area. Second, I provide evidence that the extent of new-product developments is explained by the directors' experience gained from participating in the new-product development activities of other organizations. Finally, I provide evidence that the directors' experience shapes the way in which the firm's internal experience affects the extent of new-product developments for a specific therapeutic area. These findings suggest that directors' experience may help firms overcome the constraints they face when trying to exploit their internal experience through new product developments.
520 $a In the second essay I explore how new biotechnology firms (NBFs) select pharmaceutical firms as R&D allies as a function of partner attractiveness and appropriation risks. I find that NBFs are more likely to ally with pharmaceutical firms that have the following two capabilities: (1) the ability to understand the NBF's technology (technological relatedness), and (2) strong development competences. Yet, I provide evidence showing that these positive effects of technological relatedness and a pharmaceutical firm's development experience on the likelihood of establishing an R&D alliance are negatively moderated by the pharmaceutical firm's therapeutic area diversity and the NBF's technology breadth. These findings suggest that NBFs see pharmaceutical firms' development experience and technological relatedness as increasing appropriation risks (rather than partner attractiveness) when the NBF's knowledge is broadly applicable or when the pharmaceutical firm is highly diversified across many therapeutic domains.
590 $a School code: 0208.
650 4 $a Business Administration, Entrepreneurship. $3 1026793
650 4 $a Business Administration, Management. $3 626628
690 $a 0429
690 $a 0454
710 2 $a University of Southern California. $b Business Administration. $3 1029757
773 0 $t Dissertation Abstracts International $g 70-07A.
790 1 0 $a Rajagopalan, Nandini, $e advisor
790 1 0 $a Dutta, Shantanu $e committee member
790 1 0 $a Mayer, Kyle $e committee member
790 1 0 $a Moon, Hyungsik Roger $e committee member
790 $a 0208
791 $a Ph.D.
792 $a 2009
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3368511