東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Self-assembly from the nanoscale to ...

Feinstein, Efraim David.

Linked to FindBook

Google Book

Amazon

博客來

Self-assembly from the nanoscale to the mesoscale: Applications to one-dimensional, two-dimensional, and three-dimensional tissue engineering, and to DNA sequence recognition.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Self-assembly from the nanoscale to the mesoscale: Applications to one-dimensional, two-dimensional, and three-dimensional tissue engineering, and to DNA sequence recognition./
Author:	Feinstein, Efraim David.
Description:	114 p.
Notes:	Source: Dissertation Abstracts International, Volume: 70-07, Section: B, page: 4014.
Contained By:	Dissertation Abstracts International70-07B.
Subject:	Biophysics, Medical. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3365260
ISBN:	9781109255362

Self-assembly from the nanoscale to the mesoscale: Applications to one-dimensional, two-dimensional, and three-dimensional tissue engineering, and to DNA sequence recognition.
Feinstein, Efraim David.

Self-assembly from the nanoscale to the mesoscale: Applications to one-dimensional, two-dimensional, and three-dimensional tissue engineering, and to DNA sequence recognition. - 114 p.

Source: Dissertation Abstracts International, Volume: 70-07, Section: B, page: 4014.

Thesis (Ph.D.)--Harvard University, 2009.

Creating useful, ordered structures out of disordered components is the essence of engineering. As materials reduce in size, new techniques are required to produce order at ever smaller scales. In self-assembly processes, energy sources such as thermal energy drive the initially disordered components of a system toward a stable, ordered state. The interactions between the components define the result. We may take advantage of scale-independent self-assembly processes to simplify the engineering of complex systems over orders of magnitude of size.

ISBN: 9781109255362Subjects--Topical Terms:

1017681
Biophysics, Medical.

Self-assembly from the nanoscale to the mesoscale: Applications to one-dimensional, two-dimensional, and three-dimensional tissue engineering, and to DNA sequence recognition.
LDR:03310nam 2200301 4500 001 1395923
005 20110527105422.5
008 130515s2009 ||||||||||||||||| ||eng d
020 $a 9781109255362
035 $a (UMI)AAI3365260
035 $a AAI3365260
040 $a UMI $c UMI
100 1 $a Feinstein, Efraim David. $3 1674663
245 1 0 $a Self-assembly from the nanoscale to the mesoscale: Applications to one-dimensional, two-dimensional, and three-dimensional tissue engineering, and to DNA sequence recognition.
300 $a 114 p.
500 $a Source: Dissertation Abstracts International, Volume: 70-07, Section: B, page: 4014.
500 $a Adviser: Mara Prentiss.
502 $a Thesis (Ph.D.)--Harvard University, 2009.
520 $a Creating useful, ordered structures out of disordered components is the essence of engineering. As materials reduce in size, new techniques are required to produce order at ever smaller scales. In self-assembly processes, energy sources such as thermal energy drive the initially disordered components of a system toward a stable, ordered state. The interactions between the components define the result. We may take advantage of scale-independent self-assembly processes to simplify the engineering of complex systems over orders of magnitude of size.
520 $a In this dissertation, we present three self-assembling systems. In the first, nonmagnetic particles in a magnetic fluid are self-assembled into ordered clusters. The geometry of the external magnetic field determines the cluster's ultimate geometry. The scale is limited by the magnetization of the fluid and the volumina of the particles. Such a system is useful to bioengineering applications, in cases where it is necessary to work with relatively large-scale components in the absence of a hard surface.
520 $a In the second system, we present the self assembly of an ordered fibrin lattice guided by a magnetically self-assembled two-dimensional crystal of superparamagnetic microbeads. The process relies on adhesion, linear polymerization and diffusion to extend the ordering from the nanometer scale of the fibrin fiber to the millimeter scale of the crystal. We show by simulation and experiment that the self-assembly process we describe is applicable to more general materials problems, in addition to tissue engineering.
520 $a Natural systems take advantage of self-assembly processes for life's basic functions. At the nanoscale, specificity is key to attaining the correct result of protein-protein, protein-DNA, or DNA-DNA interactions and assembly. In artificial systems, the length of the matching polymers has been a fundamental limit in achieving correct binding, and yet, in natural systems, long sequences do correctly find their matching pairs. The third system we present is a simple model of interacting, charged polymers. We propose a mechanism by which long, matching sequences can retain specificity. The proposal has implications both for how natural systems work and how to construct artificial DNA-barcode based self-assembly systems.
590 $a School code: 0084.
650 4 $a Biophysics, Medical. $3 1017681
690 $a 0760
710 2 $a Harvard University. $3 528741
773 0 $t Dissertation Abstracts International $g 70-07B.
790 1 0 $a Prentiss, Mara, $e advisor
790 $a 0084
791 $a Ph.D.
792 $a 2009
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3365260