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Optical and neural factors contribut...
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Elliott, Sarah Lynn.
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Optical and neural factors contributing to age-related losses in spatial contrast sensitivity.
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Optical and neural factors contributing to age-related losses in spatial contrast sensitivity./
Author:
Elliott, Sarah Lynn.
Description:
112 p.
Notes:
Source: Dissertation Abstracts International, Volume: 71-04, Section: B, page: 2729.
Contained By:
Dissertation Abstracts International71-04B.
Subject:
Psychology, Psychobiology. -
Online resource:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3401514
ISBN:
9781109684537
Optical and neural factors contributing to age-related losses in spatial contrast sensitivity.
Elliott, Sarah Lynn.
Optical and neural factors contributing to age-related losses in spatial contrast sensitivity.
- 112 p.
Source: Dissertation Abstracts International, Volume: 71-04, Section: B, page: 2729.
Thesis (Ph.D.)--University of California, Davis, 2009.
The purpose of this dissertation was to evaluate factors involved in age-related spatial sensitivity decline. Three experiments were conducted to examine changes in the optics of the eye and neural mechanisms operating at different levels of the human visual system.
ISBN: 9781109684537Subjects--Topical Terms:
1017821
Psychology, Psychobiology.
Optical and neural factors contributing to age-related losses in spatial contrast sensitivity.
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Optical and neural factors contributing to age-related losses in spatial contrast sensitivity.
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112 p.
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Source: Dissertation Abstracts International, Volume: 71-04, Section: B, page: 2729.
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Thesis (Ph.D.)--University of California, Davis, 2009.
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The purpose of this dissertation was to evaluate factors involved in age-related spatial sensitivity decline. Three experiments were conducted to examine changes in the optics of the eye and neural mechanisms operating at different levels of the human visual system.
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In Chapter 1, the contribution of an increase in high-order aberrations to age-related contrast sensitivity losses was measured using adaptive optics correction over a 6 mm and 3 mm pupil for 10 younger and 10 older observers. Results show that an age-related increase in high-order aberrations does contribute to the loss in spatial sensitivity, but cannot account for the complete decline. These results, in agreement with previous reports, implicate the presence of neural losses.
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Chapter 2 evaluated functional changes related to the magnocellular (M) and parvocellular (P) pathways to determine if the age-related spatial vision decline is the result of a selective neural deficit in one pathway. Contrast discrimination thresholds were measured for 10 younger and 10 older observers using two paradigms thought to separate the M and P pathways based on their contrast gain signatures. Results show large age-related functional changes in both the M and P pathways. The measured shifts in contrast gain, irrespective of pathway, could translate to behavioral changes in spatial vision.
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Chapter 3 evaluated if age-related physiological changes in cortical channel tuning extend to behavioral measures of contrast sensitivity. Contrast sensitivity functions were measured for 8 younger and 8 older observers following adaptation under three conditions: (1) a blank field, (2) a 1.5 c/deg Gabor, and (3) a 6 c/deg Gabor. Contrast sensitivity was reduced for older observers, but the tuning functions were similar for the two age groups.
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Overall, these studies indicate that both optical and neural factors contribute to age-related losses in human spatial vision. Results from Chapters 2 and 3 suggest that neural mechanisms contributing to the decline in spatial vision are generally located at pre-cortical levels. Clear discrepancies were found between younger and older observers in Chapter 2, where pre-cortical spatial vision mechanisms were targeted, whereas no differences were found in Chapter 3 in a task thought to target cortical mechanisms.
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School code: 0029.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3401514
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