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I. Introduction -- -- -- Perinatal-Neonatal Epidemiology -- -- Evaluation of Therapeutic Recommendations, Database Management, and Information Retrieval -- -- Ethical Decisions in the Neonatal-Perinatal Period -- -- II. Fetal Development -- -- -- Placental Function and Diseases: The Placenta, Fetal Membranes, and Umbilical Cord -- -- Abnormalities of Fetal Growth -- -- Hormones and Development -- -- Multiple Birth -- -- Nonimmune Hydrops -- -- III. Maternal Health Affecting Neonatal Outcome -- -- -- Endocrine Disorders in Pregnancy -- -- Maternal Medical Disorders of Fetal Significance Seizure Disorders, Isoimmunization, Cancer and Mental Disorders -- -- Hypertensive Complications of Pregnancy -- -- Perinatal Substance Abuse -- -- IV. Issues in Labor and Delivery -- -- Antepartum Fetal Assessment -- -- Prematurity: Causes and Prevention -- -- Complicated Deliveries: Overview -- -- Maternal and Fetal Anesthesia and Analgesia -- -- V. Genetics -- -- Human Genome and Relevance to Prenatal and Neonatal Screening -- -- Prenatal Genetic Diagnosis -- -- Evaluation of the Dysmorphic Infant -- -- Genetic Disorders Presenting in Newborn -- VI. Congenital Metabolic Problems -- -- Overview of Clinical Evaluation of Metabolic Disease (Case Studies) -- -- Inborn Errors of Carbohydrate, Ammonia, Amino Acid, and Organic Acid Metabolism (Case Studies) -- -- Lysosomal Storage, Peroxisomal, and Glycolosation Disorders and Smith-Lemli-Opitz Syndrome Presenting in the Neonate (Case Studies) -- -- Connective Tissue Disorders and Skeletal Dysplasias (Case Studies) -- -- VII. Evaluation and Care of the Normal Newborn -- -- Initial Evaluation: History and Physical Examination of the Newborn -- -- Routine Newborn Care -- -- Newborn Screening -- VIII. Care of the High-Risk Infant -- -- Resuscitation in the Delivery Room -- -- Temperature Regulation of the Premature Infant -- -- Acid-Base, Fluid, and Electrolyte Management -- -- Cardiovascular Compromise in the Newborn Infant -- -- Care of the Extremely Low Birth Weight Infant -- -- Pharmacologic Principles and Practicalities -- -- Neonatal Pain in the 21st Century -- -- IX. Immunology and Infections -- -- Immunology of the Fetus and Newborn -- -- Fetal-Newborn HIV Infection -- -- Viral Infections of the Fetus and Newborn -- -- Toxoplasmosis, Syphilis, Malaria, and Tuberculosis -- -- Bacterial Infections of Mother and Newborn -- -- Nosocomial Infections in the Nursery -- -- Fungal Infections in the Neonatal Intensive Care Unit -- -- X. Respiratory System -- -- Lung Development : Embryology, Growth, Maturation, Developmental Biology -- -- Control of Breathing -- -- Pulmonary Physiology of the Newborn -- -- Principles of Respiratory Monitoring and Therapy -- -- Surfactant Treatment of Respiratory Disorders -- -- Respiratory Distress Syndrome and Disorders of the Transition -- -- Respiratory Failure in the Term Infant -- -- Bronchopulmonary Dysplasia and Chronic Lung Disease -- -- Anomalies of the Airway, Mediastinum and Lung Parenchyma -- -- Disorders of the Pleura, Chest Wall, and Diaphragm -- -- XI. Cardiovascular System -- -- Nomenclature and the Segmental Approach to Congenital Heart Disease -- -- Embryology and Development of the Cardiovascular System -- -- Echocardiography in the NICU -- -- Diagnosis and Stabilization of the Newborn with Congenital Heart Disease -- -- Patent Ductus Arteriousus in the Preterm Infant -- -- Common Congenital Heart Disease--Presentation, Management and Outcomes -- -- Arrhythmias in the Fetus and Newborn: Diagnosis and Management -- -- Management of Congenital Heart Disease in the Low Birth Weight Infant -- -- Long-term Neurological Outcomes in Children with Congenital Heart Disease -- -- XII. Neurologic System -- -- Developmental Embryology, Anatomy, and Physiology of the CNS -- -- Neonatal Neuroimaging -- -- Malformations and Deformations of the Developing CNS -- -- CNS Injury and Neuroprotection -- -- Neonatal Neuromuscular Disorders -- -- Neonatal Seizures -- -- Risk Assessment and Neurodevelopmental Outcomes -- -- XIII. Nutrition -- -- Enteral Nutrition for the High-Risk Neonate -- -- Parenteral Nutrition -- -- XIV. Gastrointestinal System -- -- -- Developmental Anatomy and Physiology of the Gastrointestinal Tract -- -- Anomalies of the Gastrointestinal Tract -- -- Physiologic and Inflammatory Abnormalities of the Gastrointestinal Tract -- -- Abdominal Wall Problems -- -- Necrotizing Enterocolitis and Short Bowel Syndrome -- XV. Hematologic System and Disorders of Bilirubin Metabolism -- -- -- Developmental Biology of the Hematologic System -- -- Hemostatic Disorders of the Newborn -- -- Erythrocyte Disorders in Infancy -- -- Neonatal Leukocyte Physiology and Disorders -- -- Neonatal Hyperbilirubinemia -- XVI. Renal and Genitourinary Systems -- -- -- Renal Morphogenesis and Development of Renal Function -- -- Clinical Evaluation of Renal and Urinary Tract Disease -- -- Developmental Abnormalities of the Kidneys -- -- Developmental Abnormalities of the Genitourinary System -- -- Acute and Chronic Renal Failure -- -- Glomerulonephropathies and Disorders of Tubular Function -- -- Infection of the Urinary Tract and Vesicoureteral Reflux -- -- Renal Vascular Disease in the Newborn -- -- XVII. Endocrine Disorders -- -- Embryology, Developmental Biology, and Anatomy of the Endocrine System -- -- Disorders of Calcium and Phosphorus Metabolism -- -- Disorders of the Adrenal Gland -- -- Ambiguous Genitalia in the Newborn -- -- Disorders of the Thyroid Gland -- -- Disorders of Carbohydrate Metabolism -- -- XVIII. Orthopedic Conditions -- -- Common Neonatal Orthopedic Ailments -- -- XIX. Neoplasia -- -- Tumors and Neoplasia -- -- XX. Dermatologic Conditions -- -- Newborn Skin: Development and Basic Concepts -- -- Congenital and Hereditary Disorders of the Skin -- -- Infections of the Skin -- -- Common Newborn Dermatoses -- -- Cutaneous Congenital Defects -- XXI. The Eye -- -- Disorders of the Eye -- -- XXII. APPENDICES -- Appendix 1: Drugs -- Appendix 2: Illustrative Forms and Normal Values: Blood, CSF, Urine. |