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The quantal theory of immunity = the...

Smith, Kendall A.{me_controlnum}

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The quantal theory of immunity = the molecular basis of autoimmunity and leukemia /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The quantal theory of immunity/ Kendall A. Smith.
其他題名:	the molecular basis of autoimmunity and leukemia /
作者:	Smith, Kendall A.{me_controlnum}
出版者:	Singapore ;World Scientific Pub. Co., : c2010.,
面頁冊數:	xi, 235 p. :ill. (some col.)
標題:	Immune response. -
電子資源:	http://www.worldscientific.com/worldscibooks/10.1142/7269#t=toc
ISBN:	9789814271769 (electronic bk.)

The quantal theory of immunity = the molecular basis of autoimmunity and leukemia /
Smith, Kendall A.{me_controlnum}

The quantal theory of immunitythe molecular basis of autoimmunity and leukemia /[electronic resource] :Kendall A. Smith. - Singapore ;World Scientific Pub. Co.,c2010. - xi, 235 p. :ill. (some col.)

Includes bibliographical references and index.

This book explains how the immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none (quantal) manner. To date, there has not been a complete description of the immune system and its cells and molecules, primarily because most of the information has accumulated only in the last 40 years and our understanding has been expanding rapidly only in the last 20 years. It is now clear that the cells have evolved a way to "count" the number of foreign antigenic molecular "hits", and they only react when a critical number of events have accumulated. Subsequently, control over the reaction is transferred to a systemic lymphocytotrophic hormone system that determines the tempo, magnitude and duration of the immune reaction. This book explains in detail how the immune system, cells and molecules work for the first time. With this understanding as a basis, the pathogenesis of autoimmunity can now be understood as a mutational usurpation of the genes encoding molecules that participate in a sensitive feedback regulatory control of the immune reaction. By comparison, malignant transformation is understood as a mutational usurpation of the genes encoding the molecules that control the quantal decision to proliferate, so that normal ligand/receptor cell growth control is circumvented.

Electronic reproduction.
Singapore :
World Scientific Publishing Co.,
2010.

System requirements: Adobe Acrobat Reader.

ISBN: 9789814271769 (electronic bk.)Subjects--Topical Terms:

658009
Immune response.

LC Class. No.: QR186

Dewey Class. No.: 616.97/8

The quantal theory of immunity = the molecular basis of autoimmunity and leukemia /
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