東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

The effect of extracellular osmolali...

Antolic, AnaMaria.

Linked to FindBook

Google Book

Amazon

博客來

The effect of extracellular osmolality on cell volume and resting skeletal muscle metabolism.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	The effect of extracellular osmolality on cell volume and resting skeletal muscle metabolism./
Author:	Antolic, AnaMaria.
Description:	138 p.
Notes:	Source: Masters Abstracts International, Volume: 45-01, page: 0209.
Contained By:	Masters Abstracts International45-01.
Subject:	Biology, Cell. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MR17985
ISBN:	9780494179857

The effect of extracellular osmolality on cell volume and resting skeletal muscle metabolism.
Antolic, AnaMaria.

The effect of extracellular osmolality on cell volume and resting skeletal muscle metabolism. - 138 p.

Source: Masters Abstracts International, Volume: 45-01, page: 0209.

Thesis (M.Sc.)--Brock University (Canada), 2006.

The purpose of the current investigation was to establish an in-vitro skeletal muscle model to study acute alterations in resting skeletal muscle cell volume. Isolated, whole muscle (SOL and EDL) was dissected from Long Evans rats and incubated for 60 min in Sigma Medium-199 (resting tension (1g), bubbled with 95:5% O2:CO2, 30+/-2°C, and pH 7.4). Media osmolality was altered to simulate hypo-osmotic (190+/-10 Osm) (HYPO) or hyper-osmotic conditions (400+/-10 Osm) (HYPER) while an iso-osmotic condition (290+/-10 Osm) (CON) served as a control (n=17,19,17). Following incubation, relative muscle water content decreased with HYPER and increased with HYPO in both muscle types (p<0.05). The cross-sectional area of HYPO SOL type I and type It fibres increased (p<0.05) while the EDL type II fibre area decreased in HYPER and increased from HYPO exposure. Furthermore, HYPER exposure in both muscles lead to decreased ATP and phosphocreatine (p<0.05) and increased creatine and lactate (p<0.05) compared to CON. This isolated skeletal muscle model proved viable and demonstrated that altering extracellular osmolality could cause acute alterations in muscle water content and resting muscle metabolism.

ISBN: 9780494179857Subjects--Topical Terms:

1017686
Biology, Cell.

The effect of extracellular osmolality on cell volume and resting skeletal muscle metabolism.
LDR:02033nam 2200265 a 45 001 969254
005 20110920
008 110921s2006 eng d
020 $a 9780494179857
035 $a (UMI)AAIMR17985
035 $a AAIMR17985
040 $a UMI $c UMI
100 1 $a Antolic, AnaMaria. $3 1293308
245 1 4 $a The effect of extracellular osmolality on cell volume and resting skeletal muscle metabolism.
300 $a 138 p.
500 $a Source: Masters Abstracts International, Volume: 45-01, page: 0209.
502 $a Thesis (M.Sc.)--Brock University (Canada), 2006.
520 $a The purpose of the current investigation was to establish an in-vitro skeletal muscle model to study acute alterations in resting skeletal muscle cell volume. Isolated, whole muscle (SOL and EDL) was dissected from Long Evans rats and incubated for 60 min in Sigma Medium-199 (resting tension (1g), bubbled with 95:5% O2:CO2, 30+/-2°C, and pH 7.4). Media osmolality was altered to simulate hypo-osmotic (190+/-10 Osm) (HYPO) or hyper-osmotic conditions (400+/-10 Osm) (HYPER) while an iso-osmotic condition (290+/-10 Osm) (CON) served as a control (n=17,19,17). Following incubation, relative muscle water content decreased with HYPER and increased with HYPO in both muscle types (p<0.05). The cross-sectional area of HYPO SOL type I and type It fibres increased (p<0.05) while the EDL type II fibre area decreased in HYPER and increased from HYPO exposure. Furthermore, HYPER exposure in both muscles lead to decreased ATP and phosphocreatine (p<0.05) and increased creatine and lactate (p<0.05) compared to CON. This isolated skeletal muscle model proved viable and demonstrated that altering extracellular osmolality could cause acute alterations in muscle water content and resting muscle metabolism.
590 $a School code: 1476.
650 4 $a Biology, Cell. $3 1017686
650 4 $a Biology, Physiology. $3 1017816
650 4 $a Health Sciences, Recreation. $3 1018003
690 $a 0379
690 $a 0575
690 $a 0719
710 2 0 $a Brock University (Canada). $3 1018667
773 0 $t Masters Abstracts International $g 45-01.
790 $a 1476
791 $a M.Sc.
792 $a 2006
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MR17985