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Effects of creatine feedings on prot...

Ziegenfuss, Timothy Nathan.

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Effects of creatine feedings on protein turnover, skeletal muscle morphology, cellular hydration, and anaerobic power.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Effects of creatine feedings on protein turnover, skeletal muscle morphology, cellular hydration, and anaerobic power./
作者:	Ziegenfuss, Timothy Nathan.
面頁冊數:	100 p.
附註:	Director: Peter W. R. Lemon.
Contained By:	Dissertation Abstracts International57-09B.
標題:	Biology, Animal Physiology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9706632
ISBN:	9780591137606

Effects of creatine feedings on protein turnover, skeletal muscle morphology, cellular hydration, and anaerobic power.
Ziegenfuss, Timothy Nathan.

Effects of creatine feedings on protein turnover, skeletal muscle morphology, cellular hydration, and anaerobic power. - 100 p.

Director: Peter W. R. Lemon.

Thesis (Ph.D.)--Kent State University, 1996.

While it is well established creatine plays a central role in the regulation of energy metabolism, studies examining the exercise performance effects of oral creatine feedings in humans have yielded mixed results. Equally interesting, despite compelling in vitro evidence that creatine may act as an anabolic substance, corroborative in vivo investigations are absent from the literature. This series of experiments was designed to examine the effects of creatine supplementation on protein turnover (using ($\sp{15}

ISBN: 9780591137606Subjects--Topical Terms:

1017835
Biology, Animal Physiology.

Effects of creatine feedings on protein turnover, skeletal muscle morphology, cellular hydration, and anaerobic power.
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100 1 $a Ziegenfuss, Timothy Nathan. $3 1293176
245 1 0 $a Effects of creatine feedings on protein turnover, skeletal muscle morphology, cellular hydration, and anaerobic power.
300 $a 100 p.
500 $a Director: Peter W. R. Lemon.
500 $a Source: Dissertation Abstracts International, Volume: 57-09, Section: B, page: 5429.
502 $a Thesis (Ph.D.)--Kent State University, 1996.
520 $a While it is well established creatine plays a central role in the regulation of energy metabolism, studies examining the exercise performance effects of oral creatine feedings in humans have yielded mixed results. Equally interesting, despite compelling in vitro evidence that creatine may act as an anabolic substance, corroborative in vivo investigations are absent from the literature. This series of experiments was designed to examine the effects of creatine supplementation on protein turnover (using ($\sp{15} $n ) glycine) in experienced weight trainers (N = 3), skeletal muscle morphology (using magnetic resonance imaging) and anaerobic exercise performance (using repeated cycle sprints) in high power male (n = 10) and female (n = 10) athletes, and fluid shifts (using multifrequency bioimpedance) in aerobic and cross trained males (N = 10). Following pre-testing and random group assignment, subjects ingested 0.35 g $\cdot$ kg$\sp{-1}$ FFM $\cdot$ d$\sp{-1}$ of creatine monohydrate (Cr) or maltodextrin (P) for three days prior to post-testing (a five day period was used in the ($\sp{15} $n ) glycine study). Collectively, the results suggest acute Cr supplementation: (1) improves cycle sprint performance, (2) increases thigh muscle volume, perhaps by increasing intracellular water, and (3) may improve net (protein synthesis - protein breakdown) protein status. Specifically, statistically significant (p $<$ 0.10) increases were noted in total work during the first, and peak power during the last five of six (10-s) sprints. In addition, a 6.6% increase in skeletal muscle volume of the mid thigh was found in five of six Cr subjects (p $<$ 0.05). Multifrequency bioimpedance data suggested Cr increased total body and intracellular water by 2-3% (p $<$ 0.05). Preliminary protein metabolism data suggest Cr may improve net protein status by increasing protein synthesis and/or decreasing protein breakdown. Within the framework of these and previous experiments, it appears acute Cr ingestion can positively influence several factors related to skeletal muscle hypertrophy and the performance of repeated, explosive exercise. These effects occur regardless of sex, mode of training, or level of fitness.
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650 4 $a Biology, Animal Physiology. $3 1017835
650 4 $a Education, Physical. $3 1018000
650 4 $a Health Sciences, Nutrition. $3 1017801
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710 2 0 $a Kent State University. $3 1017419
773 0 $t Dissertation Abstracts International $g 57-09B.
790 $a 0101
790 1 0 $a Lemon, Peter W. R., $e advisor
791 $a Ph.D.
792 $a 1996
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