東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Mechanisms involved in the effect of...

Elassad, Asmaa Mohamed Saeed.

Linked to FindBook

Google Book

Amazon

博客來

Mechanisms involved in the effect of chitosan in enhancing healing.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Mechanisms involved in the effect of chitosan in enhancing healing./
Author:	Elassad, Asmaa Mohamed Saeed.
Description:	90 p.
Notes:	Adviser: Charles Mackenzie.
Contained By:	Masters Abstracts International45-03.
Subject:	Biology, Microbiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1440723

Mechanisms involved in the effect of chitosan in enhancing healing.
Elassad, Asmaa Mohamed Saeed.

Mechanisms involved in the effect of chitosan in enhancing healing. - 90 p.

Adviser: Charles Mackenzie.

Thesis (M.S.)--Michigan State University, 2006.

Chitosan is a natural biopolymer that consists of a poly beta (1-4) glucosamine. It has been described as being a wound healing accelerator. In this study, two approaches were taken to investigate the biological basis of wound healing enhancement by chitosan. Firstly, the antibacterial effect of chitosan was tested in-vitro, focusing on two bacteria strains, E.coli and S.aureus using the microbroth dilution assay and the gel diffusion test. The microbroth assay showed that chitosan and the acetic acid solvent had the same minimum inhibitory concentration (MIC) ranges. Likewise, no zone of growth inhibition was detected by gel diffusion test. In the second experimental approach, the cellular response to the intra-peritoneal implantation of chitosan pads in August rats was defined over time and compared to GelfoamRTM. In-vivo, as early as 4 hours post-implantation, the cellular response induced by chitosan was significantly more than that to the GellfoamRTM. However, the reaction declined with time with chitosan, but continued to increase to the Gellfoam RTM pads. After two weeks, there was minimum collagen deposition, i.e. minimal scarring, associated with chitosan pads compared to that of the Gelfoam pads. The cellular response to chitosan was seen to include cells of the immune system. These results support the concept that chitosan enhances wound healing.Subjects--Topical Terms:

1017734
Biology, Microbiology.

Mechanisms involved in the effect of chitosan in enhancing healing.
LDR:02224nam 2200277 a 45 001 967474
005 20110915
008 110915s2006 eng d
035 $a (UMI)AAI1440723
035 $a AAI1440723
040 $a UMI $c UMI
100 1 $a Elassad, Asmaa Mohamed Saeed. $3 1291347
245 1 0 $a Mechanisms involved in the effect of chitosan in enhancing healing.
300 $a 90 p.
500 $a Adviser: Charles Mackenzie.
500 $a Source: Masters Abstracts International, Volume: 45-03, page: 1406.
502 $a Thesis (M.S.)--Michigan State University, 2006.
520 $a Chitosan is a natural biopolymer that consists of a poly beta (1-4) glucosamine. It has been described as being a wound healing accelerator. In this study, two approaches were taken to investigate the biological basis of wound healing enhancement by chitosan. Firstly, the antibacterial effect of chitosan was tested in-vitro, focusing on two bacteria strains, E.coli and S.aureus using the microbroth dilution assay and the gel diffusion test. The microbroth assay showed that chitosan and the acetic acid solvent had the same minimum inhibitory concentration (MIC) ranges. Likewise, no zone of growth inhibition was detected by gel diffusion test. In the second experimental approach, the cellular response to the intra-peritoneal implantation of chitosan pads in August rats was defined over time and compared to GelfoamRTM. In-vivo, as early as 4 hours post-implantation, the cellular response induced by chitosan was significantly more than that to the GellfoamRTM. However, the reaction declined with time with chitosan, but continued to increase to the Gellfoam RTM pads. After two weeks, there was minimum collagen deposition, i.e. minimal scarring, associated with chitosan pads compared to that of the Gelfoam pads. The cellular response to chitosan was seen to include cells of the immune system. These results support the concept that chitosan enhances wound healing.
590 $a School code: 0128.
650 4 $a Biology, Microbiology. $3 1017734
650 4 $a Biology, Veterinary Science. $3 1021733
650 4 $a Biophysics, Medical. $3 1017681
690 $a 0410
690 $a 0760
690 $a 0778
710 2 0 $a Michigan State University. $3 676168
773 0 $t Masters Abstracts International $g 45-03.
790 $a 0128
790 1 0 $a Mackenzie, Charles, $e advisor
791 $a M.S.
792 $a 2006
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1440723