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Molecular hydrogels: Design, synthes...

Yang, Zhimou.

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Molecular hydrogels: Design, synthesis, enzymatic regulation, and biological applications.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Molecular hydrogels: Design, synthesis, enzymatic regulation, and biological applications./
Author:	Yang, Zhimou.
Description:	207 p.
Notes:	Adviser: Bing Xu.
Contained By:	Dissertation Abstracts International67-12B.
Subject:	Chemistry, Polymer. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3245375

Molecular hydrogels: Design, synthesis, enzymatic regulation, and biological applications.
Yang, Zhimou.

Molecular hydrogels: Design, synthesis, enzymatic regulation, and biological applications. - 207 p.

Adviser: Bing Xu.

Thesis (Ph.D.)--Hong Kong University of Science and Technology (People's Republic of China), 2006.

We have used the techniques of SEM, TEM, Rheology, Fluorescent spectra, CD spectra to characterize all the molecular hydrogels and also described the data of pHgel-Sol, Tgel-sol and Cmin in this thesis.Subjects--Topical Terms:

1018428
Chemistry, Polymer.

Molecular hydrogels: Design, synthesis, enzymatic regulation, and biological applications.
LDR:02166nam 2200265 a 45 001 964277
005 20110901
008 110901s2006 eng d
035 $a (UMI)AAI3245375
035 $a AAI3245375
040 $a UMI $c UMI
100 1 $a Yang, Zhimou. $3 1287338
245 1 0 $a Molecular hydrogels: Design, synthesis, enzymatic regulation, and biological applications.
300 $a 207 p.
500 $a Adviser: Bing Xu.
500 $a Source: Dissertation Abstracts International, Volume: 67-12, Section: B, page: 7114.
502 $a Thesis (Ph.D.)--Hong Kong University of Science and Technology (People's Republic of China), 2006.
520 $a We have used the techniques of SEM, TEM, Rheology, Fluorescent spectra, CD spectra to characterize all the molecular hydrogels and also described the data of pHgel-Sol, Tgel-sol and Cmin in this thesis.
520 $a In this thesis, we designed and synthesized some novel molecular hydrogelators based on short peptides or amino acids. They showed responses to environmental changes such as pH, temperature, ionic strength or catalytic reactions by enzymes. We divided the thesis into three parts. In part I, we reported the molecular hydrogels response to ligand-receptor interactions. The D-Ala-D-Ala-based hydrogels show responses to the addition of vacomycin. In part II, we talked about enzymatic regulations of molecular hydrogels. We used different enzymes (phosphatase, esterase, MMP-9, beta-lactamase) or enzymatic switch (phosphase/kinase) to control the self-assembly of small molecules in vitro or in vivo. In part III, we introduced the syntheses of novel molecular hydrogelators based on amino acids, short peptides as well as antibiotic. They formed single or multi-component hydrogels. We also reported the applications of the molecular hydrogels, including the detection of inhibitors of enzyme, removal uranium ions from the wounds on mouse, killing bacteria, etc.
590 $a School code: 1223.
650 4 $a Chemistry, Polymer. $3 1018428
690 $a 0495
710 2 0 $a Hong Kong University of Science and Technology (People's Republic of China). $3 1249812
773 0 $t Dissertation Abstracts International $g 67-12B.
790 $a 1223
790 1 0 $a Xu, Bing, $e advisor
791 $a Ph.D.
792 $a 2006
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3245375