語系:
繁體中文
English
說明(常見問題)
回圖書館首頁
手機版館藏查詢
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
Photochemical and photophysical inve...
~
Neuman, Daniel.
FindBook
Google Book
Amazon
博客來
Photochemical and photophysical investigations of newly designed supramolecular structures composed of quantum dots and nitric oxide donors.
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Photochemical and photophysical investigations of newly designed supramolecular structures composed of quantum dots and nitric oxide donors./
作者:
Neuman, Daniel.
面頁冊數:
202 p.
附註:
Adviser: Peter C. Ford.
Contained By:
Dissertation Abstracts International68-03B.
標題:
Chemistry, Inorganic. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3255188
Photochemical and photophysical investigations of newly designed supramolecular structures composed of quantum dots and nitric oxide donors.
Neuman, Daniel.
Photochemical and photophysical investigations of newly designed supramolecular structures composed of quantum dots and nitric oxide donors.
- 202 p.
Adviser: Peter C. Ford.
Thesis (Ph.D.)--University of California, Santa Barbara, 2007.
Nitric oxide (NO), a ubiquitous messenger molecule in mammalian physiology, is also known to act as a potent gamma-radiation sensitizer. For this reason, there is considerable interest in the development of thermally stable compounds capable of controllably releasing NO. Such compounds could see broad application for the enhancement of existing cancer treatment strategies. In this context, photochemically activated NO precursors are attractive given the opportunity to control the location and timing of the signal leading to release of NO. With this in mind, the work described here exploits the extraordinary light absorbing capabilities of semiconductor quantum dots (QDs) both in the single photon excitation (SPE) and two photon excitation (TPE) regimes and demonstrates their potential applicability as photosensitizers for NO releasing prodrugs.Subjects--Topical Terms:
517253
Chemistry, Inorganic.
Photochemical and photophysical investigations of newly designed supramolecular structures composed of quantum dots and nitric oxide donors.
LDR
:02982nam 2200265 a 45
001
956442
005
20110624
008
110624s2007 ||||||||||||||||| ||eng d
035
$a
(UMI)AAI3255188
035
$a
AAI3255188
040
$a
UMI
$c
UMI
100
1
$a
Neuman, Daniel.
$3
1279907
245
1 0
$a
Photochemical and photophysical investigations of newly designed supramolecular structures composed of quantum dots and nitric oxide donors.
300
$a
202 p.
500
$a
Adviser: Peter C. Ford.
500
$a
Source: Dissertation Abstracts International, Volume: 68-03, Section: B, page: 1631.
502
$a
Thesis (Ph.D.)--University of California, Santa Barbara, 2007.
520
$a
Nitric oxide (NO), a ubiquitous messenger molecule in mammalian physiology, is also known to act as a potent gamma-radiation sensitizer. For this reason, there is considerable interest in the development of thermally stable compounds capable of controllably releasing NO. Such compounds could see broad application for the enhancement of existing cancer treatment strategies. In this context, photochemically activated NO precursors are attractive given the opportunity to control the location and timing of the signal leading to release of NO. With this in mind, the work described here exploits the extraordinary light absorbing capabilities of semiconductor quantum dots (QDs) both in the single photon excitation (SPE) and two photon excitation (TPE) regimes and demonstrates their potential applicability as photosensitizers for NO releasing prodrugs.
520
$a
In this dissertation, new supramolecular structures will be described that are composed of chromium(III) complexes of cyclam (cyclam = 1,4,8,11-tetraazacyclotetradecane) both covalently bound to and electrostatically assembled on the surface of water soluble CdSe/ZnS QDs. Previous studies on the nitrito (ONO) derivatives of the chromium cyclam complexes indicated that they are photo-labile towards release of NO with quantum yields as high as 50%. However, these complexes lack absorption at long wavelengths (>600 run) where biological tissue penetration is enhanced. Investigations of the electrostatic assemblies in aqueous solution demonstrate that the Cr(III) complexes quench the QD photoluminescence (PL) obtained via either SPE (366-546 nm) or TPE (800 nm) excitation in a concentration dependent manner. Furthermore, in the electrostatic assemblies containing the dinitrito trans-Cr(cyclam)(ONO) 2+ cation and CdSe/ZnS QDs, photolysis of the assembly results in enhanced photochemical NO release (up to 50 fold more) as compared to the Cr(III) complexes alone. The photophysical and photochemical properties of these QD/chromium(III) cyclam structures are the subjects of this dissertation.
590
$a
School code: 0035.
650
4
$a
Chemistry, Inorganic.
$3
517253
690
$a
0488
710
2
$a
University of California, Santa Barbara.
$3
1017586
773
0
$t
Dissertation Abstracts International
$g
68-03B.
790
$a
0035
790
1 0
$a
Ford, Peter C.,
$e
advisor
791
$a
Ph.D.
792
$a
2007
856
4 0
$u
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3255188
筆 0 讀者評論
館藏地:
全部
電子資源
出版年:
卷號:
館藏
1 筆 • 頁數 1 •
1
條碼號
典藏地名稱
館藏流通類別
資料類型
索書號
使用類型
借閱狀態
預約狀態
備註欄
附件
W9120671
電子資源
11.線上閱覽_V
電子書
EB W9120671
一般使用(Normal)
在架
0
1 筆 • 頁數 1 •
1
多媒體
評論
新增評論
分享你的心得
Export
取書館
處理中
...
變更密碼
登入