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Association between ACE genotype and...

Charbonneau, David.

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Association between ACE genotype and skeletal muscle strength and volume, and their response to strength training in older adults.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Association between ACE genotype and skeletal muscle strength and volume, and their response to strength training in older adults./
Author:	Charbonneau, David.
Description:	144 p.
Notes:	Adviser: Stephen Roth.
Contained By:	Masters Abstracts International46-02.
Subject:	Biology, Physiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1446169
ISBN:	9780549159940

Association between ACE genotype and skeletal muscle strength and volume, and their response to strength training in older adults.
Charbonneau, David.

Association between ACE genotype and skeletal muscle strength and volume, and their response to strength training in older adults. - 144 p.

Adviser: Stephen Roth.

Thesis (M.A.)--University of Maryland, College Park, 2007.

Introduction. Previous studies have linked an insertion/deletion polymorphism in the angiotensin-converting enzyme (ACE) gene with variability in the response of muscle strength and mass to strength training, though conclusions have been inconsistent across investigations. The purpose of this study was to investigate the possible association between ACE genotype and skeletal muscle strength and volume, and their adaptation to strength training. Methods. A group of older, sedentary adults completed 10-weeks of strength training. Quadriceps muscle strength and volume were measured using one repetition maximum and computed tomography, respectively. Differences were compared among ACE genotype groups (II vs. ID+DD) by sex and race. Results. Baseline and post-training, skeletal muscle strength and volume were not significantly correlated with ACE genotype. ACE genotype was significantly associated with muscle hypertrophy in Caucasian males only (p=0.02). Conclusions. The ACE genotype was not associated with skeletal muscle strength, but was associated with muscle hypertrophy in Caucasian males.

ISBN: 9780549159940Subjects--Topical Terms:

1017816
Biology, Physiology.

Association between ACE genotype and skeletal muscle strength and volume, and their response to strength training in older adults.
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040 $a UMI $c UMI
100 1 $a Charbonneau, David. $3 1278567
245 1 0 $a Association between ACE genotype and skeletal muscle strength and volume, and their response to strength training in older adults.
300 $a 144 p.
500 $a Adviser: Stephen Roth.
500 $a Source: Masters Abstracts International, Volume: 46-02, page: .
502 $a Thesis (M.A.)--University of Maryland, College Park, 2007.
520 $a Introduction. Previous studies have linked an insertion/deletion polymorphism in the angiotensin-converting enzyme (ACE) gene with variability in the response of muscle strength and mass to strength training, though conclusions have been inconsistent across investigations. The purpose of this study was to investigate the possible association between ACE genotype and skeletal muscle strength and volume, and their adaptation to strength training. Methods. A group of older, sedentary adults completed 10-weeks of strength training. Quadriceps muscle strength and volume were measured using one repetition maximum and computed tomography, respectively. Differences were compared among ACE genotype groups (II vs. ID+DD) by sex and race. Results. Baseline and post-training, skeletal muscle strength and volume were not significantly correlated with ACE genotype. ACE genotype was significantly associated with muscle hypertrophy in Caucasian males only (p=0.02). Conclusions. The ACE genotype was not associated with skeletal muscle strength, but was associated with muscle hypertrophy in Caucasian males.
590 $a School code: 0117.
650 4 $a Biology, Physiology. $3 1017816
650 4 $a Gerontology. $3 533633
650 4 $a Health Sciences, Recreation. $3 1018003
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773 0 $t Masters Abstracts International $g 46-02.
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