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Ultrasound and exercise in skeletal ...

Markert, Chad D.

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Ultrasound and exercise in skeletal muscle regeneration.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Ultrasound and exercise in skeletal muscle regeneration./
Author:	Markert, Chad D.
Description:	53 p.
Notes:	Adviser: Steven T. Devor.
Contained By:	Dissertation Abstracts International65-07B.
Subject:	Biology, Animal Physiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3141671
ISBN:	9780496887514

Ultrasound and exercise in skeletal muscle regeneration.
Markert, Chad D.

Ultrasound and exercise in skeletal muscle regeneration. - 53 p.

Adviser: Steven T. Devor.

Thesis (Ph.D.)--The Ohio State University, 2004.

Objective. To determine whether non-thermal therapeutic ultrasound (US) and low-intensity exercise (Ex) influence skeletal muscle regeneration following a standardized contusion injury in an animal model. Hypothesis. Compared with the three other contusion injured treatment groups, which received exercise treatment alone (Ex+NoUS), ultrasound treatment alone (NoEx+US), and no treatment (NoEx+NoUS), the Ex+US group will exhibit an increase in measures of skeletal muscle regeneration. Design. Randomized control trial with blinded comparisons in a 2 x 2 factorial (ultrasound X exercise) design. Setting. Animal care facility/exercise physiology biochemistry laboratory. Participants. Twenty male Wistar rats (8 mo.) received a reproducible bilateral contusion injury to the gastrocnemius (GTN) muscles. Interventions. Ultrasound (parameters = 3 MHz, 0.1 W/cm2, 1cm2 transducer, 5 min duration/day) and exercise (20 min/day of low-intensity treadmill walking at 14 m/min). Main outcome measures. 96 hour post-injury muscle mass, contractile protein concentration, fiber cross-sectional area (CSAf), number of nuclei per fiber, and myonuclear density. Results. There was a statistical difference (p < 0.05) between injured and non-injured GTN muscles in terms of myonuclei per fiber. There were no statistical differences (p < 0.01) between the 4 treatment groups for any of the outcome measures chosen as biomarkers of skeletal muscle regeneration. Conclusions. The specific hypothesis was not supported. There is no evidence that the specific continuous ultrasound and exercise protocols investigated interact to enhance skeletal muscle regeneration following contusion injury.

ISBN: 9780496887514Subjects--Topical Terms:

1017835
Biology, Animal Physiology.

Ultrasound and exercise in skeletal muscle regeneration.
LDR:02594nam 2200301 a 45 001 947876
005 20110524
008 110524s2004 ||||||||||||||||| ||eng d
020 $a 9780496887514
035 $a (UMI)AAI3141671
035 $a AAI3141671
040 $a UMI $c UMI
100 1 $a Markert, Chad D. $3 1271344
245 1 0 $a Ultrasound and exercise in skeletal muscle regeneration.
300 $a 53 p.
500 $a Adviser: Steven T. Devor.
500 $a Source: Dissertation Abstracts International, Volume: 65-07, Section: B, page: 3248.
502 $a Thesis (Ph.D.)--The Ohio State University, 2004.
520 $a Objective. To determine whether non-thermal therapeutic ultrasound (US) and low-intensity exercise (Ex) influence skeletal muscle regeneration following a standardized contusion injury in an animal model. Hypothesis. Compared with the three other contusion injured treatment groups, which received exercise treatment alone (Ex+NoUS), ultrasound treatment alone (NoEx+US), and no treatment (NoEx+NoUS), the Ex+US group will exhibit an increase in measures of skeletal muscle regeneration. Design. Randomized control trial with blinded comparisons in a 2 x 2 factorial (ultrasound X exercise) design. Setting. Animal care facility/exercise physiology biochemistry laboratory. Participants. Twenty male Wistar rats (8 mo.) received a reproducible bilateral contusion injury to the gastrocnemius (GTN) muscles. Interventions. Ultrasound (parameters = 3 MHz, 0.1 W/cm2, 1cm2 transducer, 5 min duration/day) and exercise (20 min/day of low-intensity treadmill walking at 14 m/min). Main outcome measures. 96 hour post-injury muscle mass, contractile protein concentration, fiber cross-sectional area (CSAf), number of nuclei per fiber, and myonuclear density. Results. There was a statistical difference (p < 0.05) between injured and non-injured GTN muscles in terms of myonuclei per fiber. There were no statistical differences (p < 0.01) between the 4 treatment groups for any of the outcome measures chosen as biomarkers of skeletal muscle regeneration. Conclusions. The specific hypothesis was not supported. There is no evidence that the specific continuous ultrasound and exercise protocols investigated interact to enhance skeletal muscle regeneration following contusion injury.
590 $a School code: 0168.
650 4 $a Biology, Animal Physiology. $3 1017835
650 4 $a Health Sciences, Medicine and Surgery. $3 1017756
650 4 $a Health Sciences, Recreation. $3 1018003
650 4 $a Health Sciences, Rehabilitation and Therapy. $3 1017926
690 $a 0382
690 $a 0433
690 $a 0564
690 $a 0575
710 2 $a The Ohio State University. $3 718944
773 0 $t Dissertation Abstracts International $g 65-07B.
790 $a 0168
790 1 0 $a Devor, Steven T., $e advisor
791 $a Ph.D.
792 $a 2004
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3141671