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Gluconate metabolism in Lactobacillu...

Jenkins, Julie Kay.

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Gluconate metabolism in Lactobacillus and its role in persistence in the human intestine.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Gluconate metabolism in Lactobacillus and its role in persistence in the human intestine./
作者:	Jenkins, Julie Kay.
面頁冊數:	113 p.
附註:	Adviser: Ahmed E. Yousef.
Contained By:	Dissertation Abstracts International66-07B.
標題:	Agriculture, Food Science and Technology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3182761
ISBN:	9780542242595

Gluconate metabolism in Lactobacillus and its role in persistence in the human intestine.
Jenkins, Julie Kay.

Gluconate metabolism in Lactobacillus and its role in persistence in the human intestine. - 113 p.

Adviser: Ahmed E. Yousef.

Thesis (Ph.D.)--The Ohio State University, 2005.

Knowledge of gluconate fermentation in Lactobacillus will aid researchers in their understanding of probiotic organisms, potential prebiotic compounds and the natural human intestinal microflora. (Abstract shortened by UMI.)

ISBN: 9780542242595Subjects--Topical Terms:

1017813
Agriculture, Food Science and Technology.

Gluconate metabolism in Lactobacillus and its role in persistence in the human intestine.
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245 1 0 $a Gluconate metabolism in Lactobacillus and its role in persistence in the human intestine.
300 $a 113 p.
500 $a Adviser: Ahmed E. Yousef.
500 $a Source: Dissertation Abstracts International, Volume: 66-07, Section: B, page: 3535.
502 $a Thesis (Ph.D.)--The Ohio State University, 2005.
520 $a Knowledge of gluconate fermentation in Lactobacillus will aid researchers in their understanding of probiotic organisms, potential prebiotic compounds and the natural human intestinal microflora. (Abstract shortened by UMI.)
520 $a The demand for functional foods that provide a health benefit beyond basic nutrition is on the rise. Prebiotics are non-viable food components that promote the growth of a number of beneficial bacteria that naturally inhabit the human intestinal tract. Some of these beneficial bacteria, such as Lactobacillus and Bifidobacterium species, are capable of eliciting health benefits such as reduced incidence of lactose intolerance and diarrhea, improved immune response and reduced cancer risk. The present studies address the effect of gluconate, a component of many foods and food supplements, on human intestinal microflora. Genes involved in gluconate metabolism in Lactobacillus reuteri were characterized.
520 $a The effect of dietary gluconate supplementation on human intestinal populations of Lactobacillus, Bifidobacterium, Propionibacterium, and Escherichia coli was assessed over a 7-week period. Weekly stool samples were collected from 12 subjects and selected bacterial populations were enumerated. Colonies were subsequently grown on medium containing glucose or gluconate as the primary carbon source. At the level tested, dietary calcium gluconate did not significantly affect the overall quantity of Lactobacillus, Bifidobacterium, E. coli or Propionibacterium in most of the subjects tested. However, the proportion of gluconate-fermenting Lactobacillus and Propionibacterium strains increased upon gluconate consumption in some subjects, suggesting that a shift in species composition may occur. Speciation using the 16S-23S rRNA intergenic spacer region showed 2--6 different gluconate-fermenting Lactobacillus species in each subject and 11 different species overall.
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