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Measuring quality of life in economi...
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Adachi-Mejia, Anna Maria.
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Measuring quality of life in economic evaluations of treatment for severe mental illness.
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Measuring quality of life in economic evaluations of treatment for severe mental illness./
Author:
Adachi-Mejia, Anna Maria.
Description:
173 p.
Notes:
Chair: Robin E. Clark.
Contained By:
Dissertation Abstracts International63-07B.
Subject:
Health Sciences, Mental Health. -
Online resource:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3059801
ISBN:
0493754954
Measuring quality of life in economic evaluations of treatment for severe mental illness.
Adachi-Mejia, Anna Maria.
Measuring quality of life in economic evaluations of treatment for severe mental illness.
- 173 p.
Chair: Robin E. Clark.
Thesis (Ph.D.)--Dartmouth College, 2002.
<italic>Objective</italic>. This dissertation has two aims related to mental illness: (1) to compare disease-specific and generic health-related quality-of-life instruments, and (2) to compare societal and consumer preferences.
ISBN: 0493754954Subjects--Topical Terms:
1017693
Health Sciences, Mental Health.
Measuring quality of life in economic evaluations of treatment for severe mental illness.
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Measuring quality of life in economic evaluations of treatment for severe mental illness.
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173 p.
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Chair: Robin E. Clark.
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Source: Dissertation Abstracts International, Volume: 63-07, Section: B, page: 3223.
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Thesis (Ph.D.)--Dartmouth College, 2002.
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<italic>Objective</italic>. This dissertation has two aims related to mental illness: (1) to compare disease-specific and generic health-related quality-of-life instruments, and (2) to compare societal and consumer preferences.
520
$a
<italic>Background</italic>. It is not clear whether a generic quality-of-life instrument can appropriately represent severe mental illness in an economic evaluation. This problem is particularly salient for resource-allocation decisions where policymakers compare interventions for a variety of illnesses. Generic instruments facilitate cross-disease comparisons, but may not detect important aspects of an illness. Disease-specific instruments may detect differences unique to an illness, but do not allow comparison across diseases. Further, while the societal perspective is recommended for cost-effectiveness analysis, the relationship between societal and consumer values is not clear.
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<italic>Methods</italic>. Disease-specific and generic health-related quality-of-life instruments were compared by studying the Wisconsin Quality of Life Index (W-QLI), the SF-6D, and the EuroQol EQ-5D. Their ability to discriminate along important dimensions was compared using three criterion variables: symptom severity, need for additional substance abuse treatment, and structured activity. The consumer group was a convenience sample of 49 consumers with severe mental illness and substance use disorder. The societal group was a convenience sample of 52 New Hampshire residents. Both groups provided rating-scale values for the following quality-of-life domains: work or school; friends, family, other people they spend time with; how they feel about themselves; their physical health; having enough money; ability to take care of themselves; their mental health; their personal safety.
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<italic>Results</italic>. The W-QLI, the disease-specific instrument, was associated with the symptom-severity and need for additional substance abuse treatment criterion variables; the generic instruments, the SF-6D and the EQ-5D, were not. Controlling for mood showed no association between any of the instruments and the structured activity criterion variable. For the rating scale values, only the friends/family category showed a statistically significant difference between groups (P = 0.04).
520
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<italic>Conclusions</italic>. Based on a limited sample, this work calls into question the ability of a generic instrument to adequately discriminate differences in outcomes pertinent to mental illness. While statistical power was low, apparent differences between societal and consumer perspectives warrant further research to confirm these results.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3059801
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