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Oxygen uptake and leg blood flow at ...

MacDonald, Maureen Jane.

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Oxygen uptake and leg blood flow at the onset of kicking exercise in humans.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Oxygen uptake and leg blood flow at the onset of kicking exercise in humans./
Author:	MacDonald, Maureen Jane.
Description:	182 p.
Notes:	Adviser: Richard L. Hughson.
Contained By:	Dissertation Abstracts International59-09B.
Subject:	Applied Mechanics. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=NQ30624
ISBN:	0612306240

Oxygen uptake and leg blood flow at the onset of kicking exercise in humans.
MacDonald, Maureen Jane.

Oxygen uptake and leg blood flow at the onset of kicking exercise in humans. - 182 p.

Adviser: Richard L. Hughson.

Thesis (Ph.D.)--University of Waterloo (Canada), 1998.

The main hypothesis of this thesis was that changes in the adaptation of leg blood flow (LBF) can impact on oxygen uptake (VO$\sb2$) at the onset of moderate intensity kicking exercise. LBF and VO$\sb2$ increase rapidly at the onset of exercise in humans, however, the specific regulatory mechanisms for these processes are unknown. Three studies were conducted in which the time course of change in LBF was determined at the onset of rhythmic leg kicking exercise using Doppler ultrasound. In addition, VO$\sb2$ responses at the onset of exercise were measured. In the first study (Paper I) LBF kinetics were slowed when muscle perfusion pressure was less in the supine versus upright exercise position. This decrease in LBF kinetics in the supine position was associated with a slowing of VO$\sb2$ at the onset of exercise. The LBF response was observed to precede the VO$\sb2$ response, however, the dynamic responses of LBF and VO$\sb2$ appeared to closely parallel each other at the onset of exercise, particularly in the supine position. In a second study (Paper II), the time course of LBF and VO$\sb2$ at the onset of kicking exercise was unaffected by a single day of heavy exercise training. On the day of heavy exercise training, bouts of prior high intensity exercise resulted in an increase in the leg vascular conductance during both 0 W and 50 W exercise, but did not alter the dynamic response of LBF during transitions between the two work rate levels. In the third study (Paper III), different gas breathing conditions altered the arterial oxygen content, however, adaptations in LBF and O$\sb2$ extraction resulted in no change in oxygen delivery or in VO$\sb2$ at the onset of exercise. As part of the third study, the application of near infrared spectroscopy (NIRS) measures of Hb/Mb O$\sb2$ saturation were compared to femoral venous O$\sb2$ saturation (SfvO$\sb2$) at the onset of exercise in different gas breathing conditions (Paper IV). There was a marked separation between the directly measured SfvO$\sb2$ and the indirect estimates of Hb/Mb O$\sb2$ saturation from NIRS. Alterations in the rate of adjustment of LBF to exercising muscle at the onset of moderate intensity large muscle mass, can induce adaptations in the dynamic response of VO$\sb2$, however, regulatory mechanisms within the exercising muscles assist in maintaining LBF and VO$\sb2$ at the onset of moderate intensity kicking exercise.

ISBN: 0612306240Subjects--Topical Terms:

1018410
Applied Mechanics.

Oxygen uptake and leg blood flow at the onset of kicking exercise in humans.
LDR:03367nam 2200301 a 45 001 931547
005 20110429
008 110429s1998 eng d
020 $a 0612306240
035 $a (UnM)AAINQ30624
035 $a AAINQ30624
040 $a UnM $c UnM
100 1 $a MacDonald, Maureen Jane. $3 1255090
245 1 0 $a Oxygen uptake and leg blood flow at the onset of kicking exercise in humans.
300 $a 182 p.
500 $a Adviser: Richard L. Hughson.
500 $a Source: Dissertation Abstracts International, Volume: 59-09, Section: B, page: 4764.
502 $a Thesis (Ph.D.)--University of Waterloo (Canada), 1998.
520 $a The main hypothesis of this thesis was that changes in the adaptation of leg blood flow (LBF) can impact on oxygen uptake (VO$\sb2$) at the onset of moderate intensity kicking exercise. LBF and VO$\sb2$ increase rapidly at the onset of exercise in humans, however, the specific regulatory mechanisms for these processes are unknown. Three studies were conducted in which the time course of change in LBF was determined at the onset of rhythmic leg kicking exercise using Doppler ultrasound. In addition, VO$\sb2$ responses at the onset of exercise were measured. In the first study (Paper I) LBF kinetics were slowed when muscle perfusion pressure was less in the supine versus upright exercise position. This decrease in LBF kinetics in the supine position was associated with a slowing of VO$\sb2$ at the onset of exercise. The LBF response was observed to precede the VO$\sb2$ response, however, the dynamic responses of LBF and VO$\sb2$ appeared to closely parallel each other at the onset of exercise, particularly in the supine position. In a second study (Paper II), the time course of LBF and VO$\sb2$ at the onset of kicking exercise was unaffected by a single day of heavy exercise training. On the day of heavy exercise training, bouts of prior high intensity exercise resulted in an increase in the leg vascular conductance during both 0 W and 50 W exercise, but did not alter the dynamic response of LBF during transitions between the two work rate levels. In the third study (Paper III), different gas breathing conditions altered the arterial oxygen content, however, adaptations in LBF and O$\sb2$ extraction resulted in no change in oxygen delivery or in VO$\sb2$ at the onset of exercise. As part of the third study, the application of near infrared spectroscopy (NIRS) measures of Hb/Mb O$\sb2$ saturation were compared to femoral venous O$\sb2$ saturation (SfvO$\sb2$) at the onset of exercise in different gas breathing conditions (Paper IV). There was a marked separation between the directly measured SfvO$\sb2$ and the indirect estimates of Hb/Mb O$\sb2$ saturation from NIRS. Alterations in the rate of adjustment of LBF to exercising muscle at the onset of moderate intensity large muscle mass, can induce adaptations in the dynamic response of VO$\sb2$, however, regulatory mechanisms within the exercising muscles assist in maintaining LBF and VO$\sb2$ at the onset of moderate intensity kicking exercise.
590 $a School code: 1141.
650 4 $a Applied Mechanics. $3 1018410
650 4 $a Biology, Animal Physiology. $3 1017835
650 4 $a Health Sciences, Recreation. $3 1018003
650 4 $a Health Sciences, Rehabilitation and Therapy. $3 1017926
690 $a 0346
690 $a 0382
690 $a 0433
690 $a 0575
710 2 0 $a University of Waterloo (Canada). $3 1017669
773 0 $t Dissertation Abstracts International $g 59-09B.
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791 $a Ph.D.
792 $a 1998
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=NQ30624