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Molecular biology in medicinal chemi...

Dingermann, Theodor.

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Molecular biology in medicinal chemistry /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Molecular biology in medicinal chemistry // edited by Th. Dingermann, D. Steinhilber and G. Folkers.
其他作者:	Dingermann, Theodor.
出版者:	Weinheim :Wiley-VCH, : c2004.,
面頁冊數:	xxi, 413 p. :ill. ;24 cm.
叢書名:	Methods and principles in medical chemistry ;
內容註:	Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N -Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology.
標題:	Chiral drugs. -
ISBN:	3527304312 :

Molecular biology in medicinal chemistry /
Molecular biology in medicinal chemistry /edited by Th. Dingermann, D. Steinhilber and G. Folkers. - Weinheim :Wiley-VCH,c2004. - xxi, 413 p. :ill. ;24 cm. - Methods and principles in medical chemistry ;v. 21..

Includes bibliographical references and index.

Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N -Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology.

Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.

ISBN: 3527304312 :US200.00Subjects--Topical Terms:

686368
Chiral drugs.

Molecular biology in medicinal chemistry /
LDR:01706pam a2200181 a 45 001 698054
003 aOCoLC
005 20051114
008 051025s2004 gw a b 001 0 eng
020 $a 3527304312 : $c US200.00
035 $a CS94T0012
040 $a OHX $c OHX $d OCLCQ $d FQG
245 1 0 $a Molecular biology in medicinal chemistry / $c edited by Th. Dingermann, D. Steinhilber and G. Folkers.
260 $a Weinheim : $c c2004. $b Wiley-VCH,
300 $a xxi, 413 p. : $b ill. ; $c 24 cm.
440 0 $a Methods and principles in medical chemistry ; $v v. 21.
504 $a Includes bibliographical references and index.
505 0 $a Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N -Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology.
520 $a Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.
650 $a Chiral drugs. $3 686368
650 $a Genomics. $3 600531
650 $a Molecular biology. $3 517296
650 $a Molecular pharmacology. $3 736588
650 $a Pharmacogenomics. $3 600543
650 $a Chemistry, Pharmaceutical. $3 550957
650 $a Genetic Engineering. $3 600566
650 $a Molecular Biology. $3 600567
700 $a Dingermann, Theodor. $3 750269
700 $a Folkers, Gerd. $3 690387
700 $a Steinhilber, Dieter, $d 1959-. $3 750270