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Mother and Infant OXTR Genotypes and...

Stophaeros, Sunny Lindsley-Gene.

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Mother and Infant OXTR Genotypes and Methylation Profiles as Predictors of Maternal Postpartum Depression.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Mother and Infant OXTR Genotypes and Methylation Profiles as Predictors of Maternal Postpartum Depression./
Author:	Stophaeros, Sunny Lindsley-Gene.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2024,
Description:	57 p.
Notes:	Source: Dissertations Abstracts International, Volume: 85-11, Section: B.
Contained By:	Dissertations Abstracts International85-11B.
Subject:	Clinical psychology. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31244325
ISBN:	9798382768458

Mother and Infant OXTR Genotypes and Methylation Profiles as Predictors of Maternal Postpartum Depression.
Stophaeros, Sunny Lindsley-Gene.

Mother and Infant OXTR Genotypes and Methylation Profiles as Predictors of Maternal Postpartum Depression. - Ann Arbor : ProQuest Dissertations & Theses, 2024 - 57 p.

Source: Dissertations Abstracts International, Volume: 85-11, Section: B.

Thesis (Ph.D.)--University of Colorado at Denver, 2024.

Our lab's previous findings have shown that infant OXTR genotype predicts maternal depression, even after maternal genotype is controlled. Research on the impact of OXTR genotype on depression has shown disparate findings relating genotype, and no studies have considered infant genotype in predicting postpartum maternal depression. Mother-infant interactions are co-regulating in healthy dyads, and the infant represents a large part of the maternal environment in the early postpartum era. Epigenetics seeks to understand how gene expression is modified by the environment, and recently, some investigators have begun to explore the impact of methylation on depression, again with disparate findings. Few studies have considered the interaction between genotype and methylation, but findings from studies suggest potentially differential methylation based on genotype. This dissertation sought to explore how maternal gene expression (methylation) may be modified by the maternal environment (her infant) in the outcome of postpartum depression.{A0}

ISBN: 9798382768458Subjects--Topical Terms:

524863
Clinical psychology.
Subjects--Index Terms:

Gene expression

Mother and Infant OXTR Genotypes and Methylation Profiles as Predictors of Maternal Postpartum Depression.
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245 1 0 $a Mother and Infant OXTR Genotypes and Methylation Profiles as Predictors of Maternal Postpartum Depression.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2024
300 $a 57 p.
500 $a Source: Dissertations Abstracts International, Volume: 85-11, Section: B.
500 $a Advisor: Kaplan, Peter.
502 $a Thesis (Ph.D.)--University of Colorado at Denver, 2024.
520 $a Our lab's previous findings have shown that infant OXTR genotype predicts maternal depression, even after maternal genotype is controlled. Research on the impact of OXTR genotype on depression has shown disparate findings relating genotype, and no studies have considered infant genotype in predicting postpartum maternal depression. Mother-infant interactions are co-regulating in healthy dyads, and the infant represents a large part of the maternal environment in the early postpartum era. Epigenetics seeks to understand how gene expression is modified by the environment, and recently, some investigators have begun to explore the impact of methylation on depression, again with disparate findings. Few studies have considered the interaction between genotype and methylation, but findings from studies suggest potentially differential methylation based on genotype. This dissertation sought to explore how maternal gene expression (methylation) may be modified by the maternal environment (her infant) in the outcome of postpartum depression.{A0}
590 $a School code: 0765.
650 4 $a Clinical psychology. $3 524863
650 4 $a Behavioral psychology. $3 2122788
650 4 $a Developmental biology. $3 592588
650 4 $a Mental health. $3 534751
650 4 $a Obstetrics. $3 634501
653 $a Gene expression
653 $a Mother-infant interactions
653 $a OXTR
653 $a Postpartum depression
653 $a Methylation
690 $a 0622
690 $a 0384
690 $a 0758
690 $a 0347
690 $a 0380
710 2 $a University of Colorado at Denver. $b Psychology (Clinical Psychology). $3 2097392
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793 $a English
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